Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

cosalane

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
AbstractPurpose. The selection of cosalane (NSC 658586) by the National Cancer Institute for further development as a potential… Expand
2003
2003
PURPOSE Cosalane is a potent inhibitor of HIV replication with activity against a broad range of viral targets. However, oral… Expand
Review
2001
Review
2001
  • E. De Clercq
  • Current medicinal chemistry
  • 2001
  • Corpus ID: 23439270
Virtually all the compounds that are currently used, or under advanced clinical trial, for the treatment of HIV infections… Expand
2001
2001
Cosalane and its synthetic derivatives inhibit the binding of gp120 to CD4 as well as the fusion of the viral envelope with the… Expand
2000
2000
Cosalane is a potent inhibitor of HIV replication with activity against a broad range of viral targets. However, the oral… Expand
1999
1999
The anti-HIV agent cosalane inhibits both the binding of gp120 to CD4 as well as an undefined postattachment event prior to… Expand
1996
1996
In order to define the role of the cholestane moiety in the anti-HIV agent cosalane, a series of cosalane analogs was synthesized… Expand
1996
1996
The effects of linker chain modifications were investigated in a series of cosalane analogues. The modifications investigated… Expand
Highly Cited
1995
Highly Cited
1995
Several new analogues of the novel anti-HIV agent cosalane have been synthesized and evaluated as inhibitors of HIV-1 integrase… Expand
1994
1994
Cosalane (3), a novel anti-HIV agent having a disalicylmethane unit linked to C-3 of cholestane by a three-carbon linker, was… Expand