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cosalane

National Institutes of Health

Papers overview

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Review
2001
Review
2001
  • E. De Clercq
  • Current Medicinal Chemistry
  • 2001
  • Corpus ID: 23439270
Abstract Virtually all the compounds that are currently used, or under advanced clinical trial, for the treatment of HIV… 
2001
2001
Cosalane and its synthetic derivatives inhibit the binding of gp120 to CD4 as well as the fusion of the viral envelope with the… 
2001
2001
Cosalane is a potent inhibitor of HIV replication with multiple sites of action. The purposes of this study were to (a) determine… 
2000
2000
Cosalane is a potent inhibitor of HIV replication with activity against a broad range of viral targets. However, the oral… 
1999
1999
The anti-HIV agent cosalane inhibits both the binding of gp120 to CD4 as well as an undefined postattachment event prior to… 
1996
1996
AbstractPurpose. The selection of cosalane (NSC 658586) by the National Cancer Institute for further development as a potential… 
1996
1996
In order to define the role of the cholestane moiety in the anti-HIV agent cosalane, a series of cosalane analogs was synthesized… 
Highly Cited
1995
Highly Cited
1995
Several new analogues of the novel anti-HIV agent cosalane have been synthesized and evaluated as inhibitors of HIV-1 integrase… 
Highly Cited
1994
Highly Cited
1994
Cosalane (3), a novel anti-HIV agent having a disalicylmethane unit linked to C-3 of cholestane by a three-carbon linker, was…