cosalane
National Institutes of Health
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The potential of a large variety of new compounds and new strategies for the treatment of virtually all major virus infections…
Cosalane and its synthetic derivatives inhibit the binding of gp120 to CD4 as well as the fusion of the viral envelope with the…
Cosalane and dihydrocosalane are potent inhibitors of HIV replication with a broad range of activity. The purpose of this study…
Cosalane is a potent inhibitor of HIV replication with activity against a broad range of viral targets. However, the oral…
The anti-HIV agent cosalane inhibits both the binding of gp120 to CD4 as well as an undefined postattachment event prior to…
In order to define the role of the cholestane moiety in the anti-HIV agent cosalane, a series of cosalane analogs was synthesized…
AbstractPurpose. The selection of cosalane (NSC 658586) by the National Cancer Institute for further development as a potential…
Several new analogues of the novel anti-HIV agent cosalane have been synthesized and evaluated as inhibitors of HIV-1 integrase…
Cosalane (3), a novel anti-HIV agent having a disalicylmethane unit linked to C-3 of cholestane by a three-carbon linker, was…