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coreceptor activity

Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity… 
National Institutes of Health

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coreceptor activity involved in Wnt signaling pathwaycoreceptor activity involved in Wnt signaling pathway, planar cell polarity pathwaycoreceptor activity involved in canonical Wnt signaling pathway

Papers overview

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2004
2004
Specific inhibition of HIV-1 coreceptor activity by synthetic peptides corresponding to the predicted extracellular loops of CCR5.
We used synthetic peptides to the extracellular loops (ECLs) of CCR5 to examine inhibitory effects on HIV infection/fusion with… 
Highly Cited
2001
Highly Cited
2001
Naturally Occurring Deletional Mutation in the C-Terminal Cytoplasmic Tail of CCR5 Affects Surface Trafficking of CCR5
ABSTRACT CCR5 is an essential coreceptor for the cellular entry of R5 strains of human immunodeficiency virus type 1 (HIV-1… 
Highly Cited
2000
Highly Cited
2000
Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes.
CCR5 and CXCR4 are the major coreceptors that mediate human immunodeficiency virus 1 (HIV-1) infection, while most simian… 
2000
2000
Cell-dependent mechanisms restrict the HIV type 1 coreceptor activity of US28, a chemokine receptor homolog encoded by human cytomegalovirus.
Several members of the chemokine receptor family are used together with CD4 for HIV-1 entry into target cells. The human… 
Highly Cited
1999
Highly Cited
1999
Extracellular Cysteines of CCR5 Are Required for Chemokine Binding, but Dispensable for HIV-1 Coreceptor Activity*
CCR5 is the major coreceptor for macrophage-tropic human immunodeficiency virus type I (HIV-1). For most G-protein-coupled… 
Highly Cited
1999
Highly Cited
1999
Mutagenesis of CXCR4 Identifies Important Domains for Human Immunodeficiency Virus Type 1 X4 Isolate Envelope-Mediated Membrane Fusion and Virus Entry and Reveals Cryptic Coreceptor Activity for R5…
ABSTRACT CXCR4 is a chemokine receptor and a coreceptor for T-cell-line-tropic (X4) and dual-tropic (R5X4) human immunodeficiency… 
1999
1999
CCR5 HIV-1 Coreceptor Activity
Human (H-) CCR5 is the primary coreceptor for ENV-mediated fusion by R5 strains of human immunodeficiency virus type 1, whereas… 
Highly Cited
1998
Highly Cited
1998
CXCR4 Sequences Involved in Coreceptor Determination of Human Immunodeficiency Virus Type-1 Tropism
The interaction of human immunodeficiency virus type 1 (HIV-1) with CD4 and one of a cadre of chemokine receptors triggers… 
Review
1998
Review
1998
Structure-function studies of the HIV-1 coreceptors.
Ten seven-transmembrane-domain G protein-coupled receptors have been identified that are functional HIV-1, HIV-2 and SIV… 
Highly Cited
1997
Highly Cited
1997
Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses
CCR5, a receptor for the CC chemokines RANTES, Mip1alpha, and Mip1beta, has been identified as a coreceptor for infections by… 
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