compstatin

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2018
051019982018

Papers overview

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2013
2013
Therapeutic modulation of the complement system has become increasingly important in line with the growing recognition of the… (More)
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2007
2007
Undesired complement activation is a major cause of tissue injury in various pathological conditions and contributes to several… (More)
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2005
2005
We present new findings in our drug discovery effort to develop an anticomplement therapeutic. We have designed several active… (More)
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2003
2003
A novel structure-activity-based combinatorial computational optimization methodology for the design of peptides that are… (More)
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2003
2003
Although activation of complement protein C3 is essential for the generation of normal inflammatory responses against pathogens… (More)
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Highly Cited
2002
Highly Cited
2002
Complement plays an essential role in inflammation and tissue damage. However, it is largely unknown to what extent the system… (More)
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Highly Cited
2000
Highly Cited
2000
We have previously identified a 13-residue cyclic peptide, Compstatin, that binds to complement component C3 and inhibits… (More)
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2000
2000
Complement activation products are major components of the inflammatory response induced by cardiac surgery and cardiopulmonary… (More)
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1998
1998
The third component of complement, C3, plays a central role in activation of the classical, alternative, and lectin pathways of… (More)
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Highly Cited
1998
Highly Cited
1998
Recently, a C3-binding cyclic synthetic peptide (Compstatin) has been identified that binds to complement component C3 and… (More)
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