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commitment complex

Known as: commitment complex location 
A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript. [GOC:krc… 
National Institutes of Health

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U1 snRNP location

Papers overview

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2014
2014
An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8
Prp28 is a “DEAD-box” ATPase that promotes displacement of the U1 snRNP from the intron 5′ splice site during spliceosome… 
Highly Cited
2010
Highly Cited
2010
Invariant U2 snRNA nucleotides form a stem loop to recognize the intron early in splicing.
2009
2009
DExD/H-box Prp5 protein is in the spliceosome during most of the splicing cycle.
The DExD/H-box Prp5 protein (Prp5p) is an essential, RNA-dependent ATPase required for pre-spliceosome formation during nuclear… 
2004
2004
Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation.
The U1 small nuclear ribonucleoprotein particle U1C protein has a zinc finger-like structure (C2H2 motif) at its N terminus… 
Highly Cited
1999
Highly Cited
1999
Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complex.
In the yeast commitment complex and the mammalian E complex, there is an important base-pairing interaction between the 5' end of… 
Highly Cited
1997
Highly Cited
1997
Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals
1997
1997
The branchpoint residue is recognized during commitment complex formation before being bulged out of the U2 snRNA-pre-mRNA duplex
We have analyzed the mechanism of branchpoint nucleotide selection during the first step of pre-mRNA splicing. It has previously… 
Highly Cited
1996
Highly Cited
1996
The yeast splicing factor Mud13p is a commitment complex component and corresponds to CBP20, the small subunit of the nuclear cap-binding complex.
The mechanism by which pre-mRNAs are initially recognized by the splicing machinery is not well understood. In the yeast system… 
1994
1994
Regulation of adenovirus alternative RNA splicing at the level of commitment complex formation.
The adenovirus late region 1 (L1) represents an example of an alternatively spliced gene where one 5' splice site is spliced to… 
Highly Cited
1993
Highly Cited
1993
A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA
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