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closantel

Known as: Benzamide, N-(5-chloro-4-((4-chlorophenyl)cyanomethyl)-2-methylphenyl)-2-hydroxy-3,5-diiodo-, N-(5-chloro-4((4-chlorophenyl)cyanomethyl)-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

AnthelminticsInsecticidesSalicylanilides
Closantel Sodium

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus.
Onchocerciasis, or river blindness, is a neglected tropical disease that affects more than 37 million people worldwide, primarily… 
2002
2002
Blindness in lambs due to inadvertent closantel overdose
CLOSANTEL is a salicylanilide drug used for the treatment and control of fasciolosis in sheep and cattle. It is also active… 
Highly Cited
2000
Highly Cited
2000
Activity of closantel against adult triclabendazoleresistant Fasciola hepatica
THE first report of liver fluke (Fasciola hepatica) resistant to triclabendazole came from laboratory selection and involved… 
1999
1999
Optic neuropathy in sheep associated with overdosage of closantel.
This report describes clinical and pathological findings in 2 flocks in Brazil where blindness and deaths in sheep occurred after… 
1998
1998
Use of P-glycoprotein gene probes to investigate anthelmintic resistance in Haemonchus contortus and comparison with Onchocerca volvulus.
1995
1995
Closantel intoxication in a dog.
A case of overdosage with closantel, a salicynalide derivative, in a dog is described. The dog received 6 times the recommended… 
1994
1994
Anthelmintic resistance in Haemonchus contortus from sheep in Malaysia.
1993
1993
An outbreak of haemonchosis associated with anthelmintic resistance in sheep.
1989
1989
Effect of closantel on intrategumental pH in Schistosoma mansoni and Fasciola hepatica.
It has been proposed that the anthelmintic activity of the flukicide, closantel, is due to the drug's ability to interfere with… 
1985
1985
Toxicological properties of closantel.
The acute, subacute and chronic toxicity studies in laboratory animals showed that closantel is a well tolerated substance. At… 
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