clinofibrate

Known as: 1,1-bis(4'-(1''-carboxy-1''-methylpropoxy)phenyl)cyclohexane, butanoic acid, 2,2'-(cyclohexylidenebis(4,1-phenyleneoxy))bis(2-methyl)

A fibrate derivative with antilipidemic activity. Climofibrate has its greatest effect in reducing VLDL-triglyceride levels.

National Institutes of Health

Papers overview

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2007

1 In the present study, we evaluated fibrate‐mediated potentiation of statin‐induced apoptosis in IM‐9 human lymphoblasts. 2 The…

2007

Clinofibrate, an antilipidemic agent was synthesized from cyclohexanone by electrophilic substitution with phenol to give 1,1-bis…

1994

The present study was performed to determine the serum lipid and lipoprotein changes in cholesterol free-high fructose diet (HFD…

1994

Effects of clinofibrate on the coagulative and fibrinolytic activity in an intrinsic hyperlipidemia induced by a cholesterol free…

1991

1989

The effects of clinofibrate on serum lipoprotein concentrations, lecithin cholesterol acyl transferase activity and atherogenic…

1989

The results are reported of a double-blind crossover trial intended to evaluate the effectiveness and safety of a new aryloxy…

1988

1987

The effect of some hypolipidemic agents, which are commercially available and those being developed, on certain biochemical…

1983

Atherosclerotic lesions formed in the aorta of rats given diet containing propylthiouracil (PTU), vitamin D2 and high cholesterol…