cis-2-butene-1,4-dial
National Institutes of Health
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Furan is a liver toxicant and carcinogen in rodents. It is classified as a possible human carcinogen, but the human health…
Furan is a rodent hepatotoxicant and carcinogen. Because this compound is an important industrial intermediate and has been…
Furan is a liver toxicant and carcinogen in rodents. On the basis of these observations and the large potential for human…
The hepatocarcinogen and toxicant furan requires metabolic activation to elicit its toxic effects. The available experimental…
Furan is a liver carcinogen and toxicant. Furan is oxidized to the reactive dialdehyde, cis-2-butene-1,4-dial, by microsomal…
Furan is an environmental chemical that induces liver toxicity and tumor formation in rodents, leading to its classification as a…
Furan is a hepatic toxicant and carcinogen in rodents. Its microsomal metabolite, cis-2-butene-1,4-dial, is mutagenic in the Ames…
Furan is classified as a nongenotoxic hepatocarcinogen. It is thought to be activated to a toxic metabolite, cis-2-butene-1,4…
Metabolic activation of the hepatocarcinogen furan yields metabolites that react covalently with proteins. cis-2-Butene-1,4-dial…
The hepatocarcinogen furan is believed to be activated to the reactive aldehyde, cis-2-butene-1,4-dial, by microsomal enzymes…