Disposition and Metabolism of Cumene in F344 Rats and B6C3F1 Mice
- Ling-Jen Chen, C. Wegerski, J. M. Sanders
- Biology, MedicineDrug Metabolism And Disposition
- 1 March 2011
The absorption, distribution, metabolism, and excretion of [14C]cumene (isopropylbenzene) was studied in male rats and mice of both sexes after oral or intravenous administration and the highest tissue 14C levels in rats were observed in adipose tissue, liver, and kidney with no accumulation observed after repeat dosing up to 7 days.
DISPOSITION OF 3-CHLORO-4-(DICHLOROMETHYL)-5-HYDROXY-2(5 H )-FURANONE (MX) IN B6C3F1 MICE AND F344 RATS
- E. Lebetkin, Ling-Jen Chen, L. Burka
- Biology, ChemistryJournal of Toxicology and Environmental Health…
- 27 December 2002
MX disposition appears to be dominated by its chemical reactivity with highest concentrations of radioactivity being found at the site of administration, with high, prolonged levels ofRadioactivity in blood compared to oral dosing.
Hydrogen splittings of bis-bicyclic hydrazine radical cations
- S. Nelsen, P. Petillo, F. A. Neugebauer
- Chemistry
- 30 June 1993
1 H-NMR spectra of bis-bicyclic hydrazine radical cations allowed determination of the magnitude and sign of the proton splitting constants under ∼2 G, and assignments to position using deuterium…
Template-directed synthesis of pyridazine-containing tetracationic cyclophane for construction of [2]rotaxane
- Qiu Fang, Ling-Jen Chen, Qing-Yan Liu
- Chemistry
- 1 May 2017
Dinuclear Lanthanide-Carboxylate Compounds: Field-Induced Slow Relaxation of Magnetization for Dysprosium(III) Analogue
- Yi-Lei Li, Qing-Yan Liu, Caiming Liu, Yu-Ling Wang, Ling-Jen Chen
- Chemistry
- 9 April 2015
Three chiral dinuclear lanthanide compounds, Ln(2)(mu(2)-L)(4)(L)(2)(phen)(2) (Ln=Dy (1), Gd (2), and Er (3); phen=1,10-phenanthroline), have been synthesized using the…
Structural Information from Hydrazine Radical Cation Optical Absorption Spectra.
- S. Nelsen, H. Q. Tran, R. Ismagilov, M. Ramm, Ling-Jen Chen, D. Powell
- ChemistryJournal of Organic Chemistry
- 17 April 1998
Transition energies of the nitrogen-centered pi,pi absorption of tetraalkylhydrazine radical cations are quite sensitive to twist at the NN bond, nitrogen pyramidality, and mixing of the sigma orbitals with the pi system, so changes in E(op) caused by changes in pyramidality and sigma,pi interaction are predicted well by the calculations.
Sky-blue phosphorescent organic light-emitting diodes with dibenzo-24-crown-8 substituted iridium(III) complexes as the dopants
- Ai-hui Liang, Jun Tang, F. Huang
- Chemistry
- 1 March 2017
Fluorine-free synthesis of all-silica STT zeolite membranes for H2/CH4 separation
- Tao Zhou, Meng-Chao Shi, X. Gu
- ChemistryChemical Engineering Journal
- 1 November 2021
Chemical and enzymatic oxidation of furosemide: formation of pyridinium salts.
- Ling-Jen Chen, L. Burka
- Chemistry, BiologyChemical Research in Toxicology
- 4 October 2007
The presence of an internal nucleophile in furosemide may have a significant effect on the toxicology and possibly the pharmacology of this furan.
A practical synthesis of 2‐aminobenzothiazoles via copper(I)‐catalyzed tandem reaction of 2‐iodoanilines with isothiocyanates in ionic liquids
- Ling-Jen Chen, Bin Huang, Q. Nie, Mingzhong Cai
- Chemistry
- 1 June 2016
A copper(I)-catalyzed tandem reaction of 2-iodoanilines with isothiocyanates was achieved in hydrophobic [bmim][PF6] ionic liquid under mild conditions, generating a variety of 2-aminobenzothiazoles…
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