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cilobradine

National Institutes of Health

Papers overview

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2012
2012
To develop a semi-mechanistic population pharmacokinetic/pharmacodynamic (PKPD) model for the selective bradycardic agent… 
2011
2011
Hyperpolarization-activated, cyclic nucleotide-gated (HCN) channels generate the rhythmic beating of mammalian hearts. We… 
2010
2010
Ivabradine represents a novel heart-rate-lowering agent that acts on the sino-atrial node supposedly by selectively inhibiting… 
2008
2008
PurposeTo evaluate the population pharmacokinetic characteristics of cilobradine including a covariate analysis based on six… 
2008
2008
Aims/hypothesisThe hyperpolarisation-activated cyclic nucleotide-gated (HCN) channels, discovered initially in cardiac and… 
2003
2003
The present invention provides the use in a pharmaceutical composition of a specific cyclic amine derivative, or its…