ciglitazone

Known as: 5-(4-(1-methylcyclohexylmethoxy)benzyl)thiazolidine-2,4-dione, ciglitizone 
An agent belonging to the glitazone (thiazolidinedione) class of antidiabetic agents with antihyperglycemic activity. Ciglitazone also exerts anti… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1983-2017
0204019832017

Papers overview

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2009
2009
Activation of PPARgamma by synthetic ligands, thiazolidinediones, inhibits the proliferation of cancer cells. In this report… (More)
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2004
2004
Glioblastoma multiforme is the most common malignant brain tumor in adults, and it is among the most lethal of all cancers… (More)
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Highly Cited
2003
Highly Cited
2003
Peroxisome proliferator activator receptor-gamma (PPARgamma) is a nuclear receptor that controls the expression of several genes… (More)
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Highly Cited
2003
Highly Cited
2003
Long-chain fatty acids (FA) coordinately induce the expression of a panel of genes involved in cellular FA metabolism in cardiac… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND C-reactive protein (CRP) induces adhesion molecule expression by endothelial cells. However, the effects of CRP on… (More)
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Highly Cited
2000
Highly Cited
2000
During liver injury, hepatic stellate cells (HSC) acquire a myofibroblast-like phenotype associated with reduction of lipid… (More)
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Highly Cited
1999
Highly Cited
1999
Peroxisome proliferator-activated receptor gamma (PPARgamma) is a nuclear receptor that functions as a transcription factor to… (More)
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Highly Cited
1999
Highly Cited
1999
In osteoporosis, the bone marrow stroma osteogenic cell population declines and adipocyte numbers increase. We recently showed… (More)
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Highly Cited
1999
Highly Cited
1999
An early event in acute and chronic inflammation and associated diseases such as atherosclerosis and rheumatoid arthritis is the… (More)
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Highly Cited
1998
Highly Cited
1998
Troglitazone, a thiazolidinedione derivative, is a widely used antidiabetic drug that binds and activates peroxisome proliferator… (More)
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