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chromatinolysis

National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
DNA damage-activated nuclease identified Cells that experience stresses and accumulate excessive damage to DNA undergo cell death… 
Highly Cited
2014
Highly Cited
2014
Significance Excessive activation of poly(ADP-ribose) (PAR) polymerase (PARP) is intimately linked to cell death in a variety of… 
Highly Cited
2012
Highly Cited
2012
Alkylating DNA-damage agents such as N-methyl-N′-nitro-N′-nitrosoguanidine (MNNG) trigger necroptosis, a newly defined form of… 
Highly Cited
2010
Highly Cited
2010
Programmed necrosis induced by DNA alkylating agents, such as MNNG, is a caspase‐independent mode of cell death mediated by… 
Highly Cited
2004
Highly Cited
2004
Cyclophilin A (CypA) was determined to interact with apoptosis-inducing factor (AIF) by mass spectroscopy, coimmunoprecipitation… 
Highly Cited
2004
Highly Cited
2004
Apoptosis‐inducing factor (AIF) is a mitochondrial flavoprotein that, after apoptosis induction, translocates to the nucleus… 
Highly Cited
2000
Highly Cited
2000
Apoptosis inducing factor (AIF) is a novel apoptotic effector protein that induces chro‐matin condensation and large‐scale (—50… 
1999
1999
We recently demonstrated that physiological induction of apoptosis by cytotoxic sphingolipid messengers proceeds via activating…