cholesterol metabolism

Known as: cholesterol metabolic process 
The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many… (More)

Topic mentions per year

Topic mentions per year

1937-2018
010020019372017

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Chronic inflammation of the arterial wall is a key element in the pathogenesis of atherosclerosis, yet the factors… (More)
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Highly Cited
2007
Highly Cited
2007
Mutations in the amyloid precursor protein (APP) cause early-onset Alzheimer's disease (AD), but the only genetic risk factor for… (More)
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Highly Cited
2004
Highly Cited
2004
Alzheimer's disease (AD) is an age-related disorder characterized by deposition of amyloid beta-peptide (Abeta) and degeneration… (More)
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Highly Cited
2003
Highly Cited
2003
The liver X receptors (LXR) alpha and beta are regulators of cholesterol metabolism and determinants of atherosclerosis… (More)
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Highly Cited
2001
Highly Cited
2001
Maturity-onset diabetes of the young type 3 (MODY3) is caused by haploinsufficiency of hepatocyte nuclear factor-1α (encoded by… (More)
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Highly Cited
2001
Highly Cited
2001
The nuclear oxysterol-receptor paralogues LXRalpha and LXRbeta share a high degree of amino acid identity and bind endogenous… (More)
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Highly Cited
1999
Highly Cited
1999
The turnover of cholesterol in the brain is thought to occur via conversion of excess cholesterol into 24S-hydroxycholesterol, an… (More)
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Highly Cited
1995
Highly Cited
1995
In this study, we compared cholesterol efflux mediated by either high density lipoproteins (HDL3) or beta-cyclodextrins, cyclic… (More)
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Highly Cited
1990
Highly Cited
1990
To investigate the regulation of serum levels of cholesterol precursor sterols and plant sterols, these noncholesterol sterols… (More)
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Highly Cited
1976
Highly Cited
1976
Cultured fibroblasts derived from patients with homozygous familial hypercholesterolemia, which lack functional low density… (More)
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