cholesterol esterification

A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the… (More)
National Institutes of Health

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Highly Cited
2016
Highly Cited
2016
CD8+ T cells have a central role in antitumour immunity, but their activity is suppressed in the tumour microenvironment… (More)
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Highly Cited
2010
Highly Cited
2010
Niemann-Pick type C disease (NPC) is a lysosomal storage disorder causing accumulation of unesterified cholesterol in lysosomal… (More)
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Highly Cited
2004
Highly Cited
2004
In individuals with type 2 diabetes, metabolic syndrome, and the combined dyslipidemia, cardiovascular risk is increased by a… (More)
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Highly Cited
1997
Highly Cited
1997
Cholesterol esterification, catalyzed by acyl-CoA:cholesterol acyltransferase (ACAT), plays a central role in cellular… (More)
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Highly Cited
1996
Highly Cited
1996
The microsomal enzyme acyl-CoA:cholesterol acyltransferase (ACAT; EC 2.3.1.26) catalyzes the esterification of cellular… (More)
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Highly Cited
1996
Highly Cited
1996
The sterol binding agent 2-hydroxypropyl-beta-cyclodextrin is shown to be a convenient and useful experimental tool to probe… (More)
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Highly Cited
1995
Highly Cited
1995
Lecithin:cholesterol acyltransferase (LCAT) and cholesteryl ester transfer protein (CETP) are responsible for the esterification… (More)
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Highly Cited
1991
Highly Cited
1991
The human cholesteryl ester transfer protein (CETP) facilitates the exchange of neutral lipids among lipoproteins. In order to… (More)
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Highly Cited
1989
Highly Cited
1989
Niemann-Pick disease type C (NPC) is characterized by substantial intracellular accumulation of unesterified cholesterol. The… (More)
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Highly Cited
1987
Highly Cited
1987
One characteristic of type C Niemann-Pick (NPC) disease is the substantial intracellular accumulation of unesterified cholesterol… (More)
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