cholesterol biosynthesis

Known as: biosynthesis cholesterol, cholesterol anabolism, cholesterol synthesis 
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Cholesterol is an essential component of cell membranes and the precursor for the synthesis of steroid hormones and bile acids… (More)
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Cholesterol metabolism is tightly regulated at the cellular level. Here we show that miR-33, an intronic microRNA (miRNA) located… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Niemann-Pick C1 Like 1 (NPC1L1) is a protein localized in jejunal enterocytes that is critical for intestinal cholesterol… (More)
  • table I
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2002
Review
2002
  • Ira Tabas
  • The Journal of clinical investigation
  • 2002
cells of most organs and tissues satisfy their requirements for membrane cholesterol via endogenous cholesterol biosynthesis (1… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Two ATP-binding cassette (ABC) transporters, ABCG5 and ABCG8, have been proposed to limit sterol absorption and to promote… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
1995
Review
1995
Objectives: I. Describe how excess carbohydrate and/or amino acid consumption leads to fatty acid and triacylglycerol production… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
BACKGROUND The Smith-Lemli-Opitz syndrome (frequency, 1:20,000 to 1:40,000) is defined by a constellation of severe birth defects… (More)
Is this relevant?
Highly Cited
1987
Highly Cited
1987
A highly purified rat liver protein kinase phosphorylates and inactivates acetyl-CoA carboxylase, and causes rapid inactivation… (More)
Is this relevant?
Review
1986
Review
1986
In 1901 a physician, Archibald Garrod, observed a patient with black urine. He used this simple observation to demonstrate that a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1976
Highly Cited
1976
Cultured fibroblasts derived from patients with homozygous familial hypercholesterolemia, which lack functional low density… (More)
Is this relevant?