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cholesterol biosynthesis
Known as:
biosynthesis cholesterol
, cholesterol anabolism
, cholesterol synthesis
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The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the…
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National Institutes of Health
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Related topics
Related topics
2 relations
Steroid biosynthesis
regulation of cholesterol biosynthetic process
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
1986
Review
1986
Atherosclerosis: an insulin-dependent disease?
N. W. Flodin
Journal of the American College of Nutrition
1986
Corpus ID: 27051591
Evidence is reviewed that dietary habits in industrially developed countries, especially an increased frequency of ingestion of…
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1977
1977
Regulation of hydroxymethylglutaryl-CoA reductase in rat leukocytes.
N. L. Young
,
V. Rodwell
Journal of Lipid Research
1977
Corpus ID: 25878710
Methods were developed for the assay of hydroxymethylglutaryl-CoA reductase (NADPH) activity in microsomes from rat leukocytes…
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1974
1974
Restraint of cholesterol accumulation in tissue pools associated with drastic short-term lowering of serum cholesterol levels by clofibrate or cholestyramine in hypercholesterolemic swine.
Dong Nack Kim
,
K. T. Lee
,
J. M. Reiner
,
W. A. Thomas
Journal of Lipid Research
1974
Corpus ID: 28775906
In this study, young growing swine were made hypercholesterolemic (~300 mg/dl) by feeding milk and eggs for 7 wk. They were then…
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1973
1973
The rôle of cytochrome P-450 in cholesterol biosynthesis.
G. Gibbons
,
Konstantinos A. Mitropoulos
European Journal of Biochemistry
1973
Corpus ID: 34379229
The rates of cholesterol biosynthesis were studied in rat liver microsomal preparations incubated with [14C]lanosterol in the…
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1972
1972
Effect of adrenalectomy on the diurnal variation of hepatic cholesterogenesis in the rat.
Peter E. Hickman
,
B. Horton
,
John R. Sabine
Journal of Lipid Research
1972
Corpus ID: 34162366
The diurnal variation in cholesterol synthesis exhibited by rat liver has been examined in fed, fasted, and adrenalectomized…
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Highly Cited
1971
Highly Cited
1971
Cholesterol biosynthesis in transplantable hepatomas: evidence for impairment of uptake and storage of dietary cholesterol.
D. Harry
,
H. Morris
,
N. McIntyre
Journal of Lipid Research
1971
Corpus ID: 23330367
Cholesterol feeding inhibits cholesterol biosynthesis in normal but not in malignant liver tissue. It has been postulated that…
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Highly Cited
1966
Highly Cited
1966
Sites of control of hepatic cholesterol biosynthesis.
R. Gould
,
E. A. Swyryd
Journal of Lipid Research
1966
Corpus ID: 33588648
An inhibition in the conversion of mevalonate to cholesterol has been demonstrated in liver of cholesterol-fed rats by both in…
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Highly Cited
1960
Highly Cited
1960
Time of occurrence of changes in the liver's capacity to utilize acetate for fatty acid and cholesterol synthesis after fat feeding.
R. Hill
,
W. W. Webster
,
J. Linazasoro
,
I. Chaikoff
1960
Corpus ID: 83841316
1959
1959
Effect of saturated and unsaturated fats on hepatic synthesis and biliary excretion of cholesterol by the rat.
Jean D. Wilson
,
Marvin D. Siperstein
American Journal of Physiology
1959
Corpus ID: 26450923
In an attempt to elucidate the mechanisms by which saturated and unsaturated fats influence cholesterol metabolism, cholesterol…
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1954
1954
Utilization of branched chain acids in cholesterol synthesis.
K. Bloch
,
L. C. Clark
,
Isaac Harary
Journal of Biological Chemistry
1954
Corpus ID: 29289885
Following the demonstration that acetic acid serves as a precursor in the biosynthesis of the steroids, considerable effort has…
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