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channel activity

Known as: channel/pore class transporter activity, nonselective channel activity 
Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel… 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Regulation of single inositol 1,4,5‐trisphosphate receptor channel activity by protein kinase A phosphorylation
Phosphorylation of inositol 1,4,5‐trisphosphate receptors (InsP3R) by PKA represents an important, common route for regulation of… 
Highly Cited
2003
Highly Cited
2003
Polycystin-1 Activates and Stabilizes the Polycystin-2 Channel*
Autosomal dominant polycystic kidney disease (ADPKD) is a prevalent genetic disorder largely caused by mutations in the PKD1 and… 
Highly Cited
1998
Highly Cited
1998
pH-dependent modulation of the cloned renal K+ channel, ROMK.
pH is an important modulator of the low-conductance ATP-sensitive K+ channel of the distal nephron. To examine the mechanism of… 
Highly Cited
1993
Highly Cited
1993
Antibodies as probes for Ca2+ activation sites in the Ca2+ release channel (ryanodine receptor) of rabbit skeletal muscle sarcoplasmic reticulum.
Highly Cited
1992
Highly Cited
1992
Cellular differentiation is required for cAMP but not Ca(2+)-dependent Cl- secretion in colonic epithelial cells expressing high levels of cystic fibrosis transmembrane conductance regulator.
Highly Cited
1989
Highly Cited
1989
Kinetic time constants independent of previous single-channel activity suggest Markov gating for a large conductance Ca-activated K channel
Models for the gating of ion channels usually assume that the rate constants for leaving any given kinetic state are independent… 
Highly Cited
1986
Highly Cited
1986
Chloride channel regulation in secretory epithelia.
Patch-clamp techniques were applied for single-channel recording to cultured cells from Cl secretory epithelia: human airway… 
Highly Cited
1985
Highly Cited
1985
Modulation of single Ca2+-dependent K+-channel activity by protein phosphorylation
There is considerable evidence that cyclic AMP can modulate the electrical activity of excitable cells1–10 and that protein… 
Highly Cited
1983
Highly Cited
1983
Hemodynamic and humoral effects of coffee after β1‐selective and nonselective β‐blockade
Several studies report a substantial rise in plasma catecholamines after caffeine. Epinephrine infusion induces a pressor… 
Highly Cited
1982
Highly Cited
1982
Effect of low‐dose epinephrine infusion on hemodynamics after selective and nonselective β‐blockade in hypertension
We studied hemodynamic effects of low doses of epinephrine in five hypertensive patients receiving long‐term treatment with… 
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