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Stability and biotransformation of various dietary anthocyanins in vitro
TLDR
Glycosylated and acylated anthocyanins were rapidly degraded by the intestinal microflora after anaerobic incubation with a human faecal suspension, indicating a rapid degradation could be one major reason for the poor bioavailability of anthcyanins in pharmacokinetic studies. Expand
Dietary synbiotics reduce cancer risk factors in polypectomized and colon cancer patients.
TLDR
The prebiotic concept as induced by a synbiotic preparation-oligofructose-enriched inulin + Lactobacillus rhamnosus GG (LGG) and Bifidobacterium lactis Bb12 (BB12)-is able to reduce the risk of colon cancer in humans. Expand
Altered regulation of airway epithelial cell chloride channels in cystic fibrosis.
TLDR
The findings demonstrate the presence of chloride channels in the apical membranes of CF airway cells, which appears to be intact, but cyclic adenosine monophosphate (cAMP)-dependent control of their activity is defective. Expand
Protective role of probiotics and prebiotics in colon cancer.
TLDR
Some of the newer studies showed that short-lived metabolite mixtures isolated from milk that was fermented with strains of Lactobacillus bulgaricus and Streptococcus thermophilus are more effective in deactivating etiologic risk factors of colon carcinogenesis than are cellular components of microorganisms. Expand
Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element.
TLDR
The results lead to the conclusion that phytoestrogens differ not only in their binding affinities for the ER, but also in their potential to increase the rate of receptor binding to the ERE. Expand
Consumption of vegetables reduces genetic damage in humans: first results of a human intervention trial with carotenoid-rich foods.
TLDR
The hypothesis that carotenoid containing plant products exert a cancer-protective effect via a decrease in oxidative and other damage to DNA in humans is supported. Expand
Apical membrane chloride channels in a colonic cell line activated by secretory agonists.
TLDR
The ability of various anions to undergo transepithelial secretion is determined by the selectivity of the basolateral membrane Cl entry step rather than by the apical Cl channel, which suggests that this cAMP-stimulated Cl channel is uniquely present in theApical membranes of salt-secreting epithelial cells. Expand
Malvidin-3-glucoside bioavailability in humans after ingestion of red wine, dealcoholized red wine and red grape juice
TLDR
M-3-G is poorly absorbed after a single ingestion of red wine, dealcoholized redwine, or red grape juice and seems to be differentially metabolized as compared to other red grape polyphenols. Expand
Prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis modulates intestinal immune functions in rats.
TLDR
The PRO supplement modestly affected immune functions, whereas systemic immunomodulatory effects were observed in rats fed SYN, which primarily acted at the level of the gut-associated lymphoid tissue. Expand
Nitrate and nitrite in the diet: how to assess their benefit and risk for human health.
TLDR
In this review, the known beneficial and detrimental health effects related to dietary nitrate/nitrite intake are described and the identified gaps in knowledge as well as the research needs required to perform a reliable benefit/risk assessment in terms of long-term human health consequences are presented. Expand
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