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chaetoglobosin K

 
National Institutes of Health

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2015
2015
Adverse side effects and acquired resistance to conventional platinum based chemotherapy have become major impediments in ovarian… Expand
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2013
2013
Ovarian cancer is the fifth leading cause of cancer deaths for women in America. With no known carcinogens or manageable risk… Expand
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2013
2013
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC Ovarian cancer is the 5th leading cause of cancer… Expand
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2012
2012
SummaryChaetoglobosin K (ChK) is a natural product that inhibits anchorage-dependent and anchorage-independent growth of ras… Expand
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2007
2007
PurposeThe purpose of the present study was to identify the biochemical mechanism(s) of the preventative and reversal effects of… Expand
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2005
2005
Purpose: Chaetoglobosin K (ChK), a bioactive natural product previously shown to have anti-tumor promoting activity in glial… Expand
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2001
2001
Innumerable toxic substances present in the environment inhibit gap junctions, intercellular membrane channels that play… Expand
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2000
2000
A rhodacyanine dye called MKT-077 has shown a highly selective toxicity toward several distinct human malignant cell lines… Expand
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1999
1999
UNLABELLED For transforming normal fibroblasts to malignant cells, oncogenic Ras mutants such as v-Ha-ras require Rho family… Expand
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Review
1999
Review
1999
Several distinct peptides or drugs that block the Rho family GTPases-mediated pathways were found to suppress RAS-induced… Expand
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