cethrin

Context: Spinal cord injury (SCI) is a devastating condition that can lead to significant neurological impairment and reduced… Expand

Traumatic spinal cord injury (SCI) is a devastating condition of motor, sensory, and autonomic dysfunction. The significant cost… Expand

Traumatic spinal cord injury (SCI) represents a significant burden of illness, but it is relatively uncommon and heterogeneous… Expand

BACKGROUND Traumatic spinal cord injuries (SCI) have devastating consequences for the physical, financial, and psychosocial well… Expand

The development of novel pharmaceutical treatments for disorders of the cerebral vasculature is a serious unmet medical need… Expand

The Cethrin™ clinical trial was an open-label Phase I/IIa trial undertaken to assess the safety, tolerability, and neurological… Expand

Multiple lines of evidence have validated the Rho pathway as important in controlling the neuronal response to growth inhibitory… Expand

Barriers to regeneration in the CNS are increasingly understood, and several are now being targeted in human clinical trials… Expand

Acute traumatic spinal cord injury (SCI) results in a devastating loss of neurological function below the level of injury and… Expand

As our understanding of the pathophysiology of spinal cord injury deepens, novel neuroprotective agents are being developed, some… Expand