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centromere protein F

Known as: CENP-F protein, Cell-Cycle-Dependent 350K Nuclear Protein, AH Antigen 
Centromere protein F (3210 aa, ~368 kDa) is encoded by the human CENPF gene. This protein plays a role in cell cycle progression and is required for… 
National Institutes of Health

Related topics

Related topics

13 relations
CENPF geneCell Cycle ControlCell divisionGenes, Regulator

Narrower (1)

Cenpf protein, mouse

Broader (2)

Chromosomal Proteins, Non-HistoneMicrofilament Proteins

Papers overview

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Highly Cited
2018
Highly Cited
2018
Centromere protein F (CENPF), a microtubule binding protein, modulates cancer metabolism by regulating pyruvate kinase M2 phosphorylation signaling
ABSTRACT Prostate cancer (PC) is the most commonly diagnosed cancer in men and is the second leading cause of male cancer-related… 
Highly Cited
2017
Highly Cited
2017
Identification of Biomarkers Correlated with the TNM Staging and Overall Survival of Patients with Bladder Cancer
Objective: To identify candidate biomarkers correlated with clinical prognosis of patients with bladder cancer (BC). Methods… 
Highly Cited
2016
Highly Cited
2016
SUMO-targeted ubiquitin ligase (STUbL) Slx5 regulates proteolysis of centromeric histone H3 variant Cse4 and prevents its mislocalization to euchromatin
A new posttranslational modification is found of centromeric histone H3 variant Cse4. Cse4 is sumoylated by E3 ligases Siz1 and… 
Highly Cited
2015
Highly Cited
2015
The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes
Background Mutations in microtubule-regulating genes are associated with disorders of neuronal migration and microcephaly… 
Highly Cited
2010
Highly Cited
2010
Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma
BackgroundTumor cell proliferation is a predictor of survival in cutaneous melanoma. The aim of the present study was to evaluate… 
Highly Cited
2007
Highly Cited
2007
Nudel modulates kinetochore association and function of cytoplasmic dynein in M phase.
The microtubule-based motor cytoplasmic dynein/dynactin is a force generator at the kinetochore. It also transports proteins away… 
Highly Cited
2005
Highly Cited
2005
Silencing Mitosin Induces Misaligned Chromosomes, Premature Chromosome Decondensation before Anaphase Onset, and Mitotic Cell Death
ABSTRACT Mitosin (also named CENP-F) is a large human nuclear protein transiently associated with the outer kinetochore plate in… 
2005
2005
Mitosin/CENP-F as a Negative Regulator of Activating Transcription Factor-4*
Mitosin/CENP-F is a human nuclear matrix protein with multiple leucine zipper motifs. Its accumulation in S-G2 phases and… 
1999
1999
The Cloning and Analysis of LEK1 Identifies Variations in the LEK/Centromere Protein F/Mitosin Gene Family*
We report the cloning of a novel murine cDNA, LEK1, that is related to human CENP-F and mitosin and more distantly to chicken… 
Highly Cited
1995
Highly Cited
1995
The C Terminus of Mitosin Is Essential for Its Nuclear Localization, Centromere/Kinetochore Targeting, and Dimerization (*)
Mitosin is a novel 350-kDa nuclear phosphoprotein that dramatically relocates from the evenly nuclear distribution in S phase to… 
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