cellular protein catabolic process

Ubiquilin (UBQLN), a member of the ubiquitin-like (UBL)-ubiquitin-associated (UBA) family, is a dual regulator of both the… (More)

Lentiviruses contain accessory genes that have evolved to counteract the effects of host cellular defence proteins that inhibit… (More)

Exposure of C. elegans to hypertonic stress-induced water loss causes rapid and widespread cellular protein damage. Survival in… (More)

The intracellular accumulation of unfolded or misfolded proteins is believed to contribute to aging and age-related… (More)

Parkinson's disease (PD) is a common movement disorder marked by the loss of dopaminergic (DA) neurons in the brain stem and the… (More)

The intracellular accumulation of unfolded or misfolded proteins is believed to contribute to aging and age-related… (More)

PURPOSE OF REVIEW The maintenance of protein balance is essential for the proper functioning of a cell. Protein degradation must… (More)

Proteasomes are essential components of the cellular protein degradation machinery. They are nonlysosomal and their participation… (More)

Bestatin, a dipeptide analog, is a potent aminopeptidase inhibitor of bacterial origin. We have previously shown that bestatin… (More)

Eukaryotic cells contain a major intracellular proteolytic activity known as the proteasome. The proteasome is a strongly… (More)