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cellular lactam biosynthetic process

Known as: cellular lactam anabolism, cellular lactam formation, cellular lactam synthesis 
The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2… 
National Institutes of Health

Papers overview

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2012
2012
Discovery of diphenyl lactam derivatives as N-type calcium channel blockers.
2011
2011
Controlled rearrangement of lactam-tethered allenols with brominating reagents: a combined experimental and theoretical study on α- versus β-keto lactam formation.
N-Bromosuccinimide (NBS) smoothly promotes the ring expansion of lactam-tethered allenols to efficiently afford cyclic α- or… 
2007
2007
Stereocontrolled access to orthogonally protected anti,anti-4-aminopiperidine-3,5-diols through chemoselective reduction of enantiopure beta-lactam cyanohydrins.
The cyanosilylation of enantiopure 4-oxoazetidine-2-carbaldehydes with tert-butyldimethylsilyl cyanide was promoted by either… 
2006
2006
A Novel Enzyme Conferring Streptothricin Resistance Alters the Toxicity of Streptothricin D from Broad-spectrum to Bacteria-specific*
Streptothricins (STs) produced by Streptomyces strains are broad-spectrum antibiotics. All STs consist of a carbamoylated d… 
2005
2005
Synthesis of pipecolic acid-based spiro bicyclic lactam scaffolds as beta-turn mimics.
A series of 6.5.5 spiro bicyclic lactam scaffolds were synthesized from pipecolic acid in a sequence of reactions that was… 
2003
2003
Pyrrolidine-5,5-trans-lactams. 5. Pharmacokinetic optimization of inhibitors of hepatitis C virus NS3/4A protease.
[reaction: see text] In this, the second of two Letters, the optimization of the pyrrolidine-5,5-trans-lactam template… 
2000
2000
Synthesis of highly potent second-generation taxoids through effective kinetic resolution coupling of racemic beta-lactams with baccatins.
A series of highly potent second-generation taxoids bearing a 2-methylprop-1-enyl or a 2-methylpropyl group at C-3' with… 
1999
1999
Synthesis of L-4,4-difluoroglutamic acid via electrophilic difluorination of a lactam.
[formula: see text] An enantiomerically pure bicyclic lactam proved to be an excellent substrate for electrophilic difluorination… 
1992
1992
New approaches in asymmetric synthesis using γ-alkoxybutenolides
Abstract 
1984
1984
Intestinal absorption of several beta-lactam antibiotics. V. Effect of amino beta-lactam analogues and dipeptides on the absorption of amino beta-lactam antibiotics.
The absorption mechanism of amino beta-lactam antibiotics was investigated by using the whole small intestine of a rat. Mutual… 
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