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ceftezole

Known as: (6R,7R)-8-Oxo-7-(2-(1H-tetrazol-1-yl)acetamido)-3-((1,3,4-thiadiazol-2-ylthio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, Ceftezol, demethylcefazolin 
A semisynthetic first-generation cephalosporin with antibacterial activity. Ceftezole binds to and inactivates penicillin-binding proteins (PBPs… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (2)

Anti-Bacterial AgentsCefazolin

Narrower (3)

CeloslinFalomesinceftezole sodium
analogs & derivatives

Papers overview

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Highly Cited
2015
Highly Cited
2015
A gold immunochromatographic assay for the rapid and simultaneous detection of fifteen β-lactams.
A novel gold immunochromatographic assay (GICA) based on anti-β-lactam receptors was innovatively developed that successfully… 
Highly Cited
2013
Highly Cited
2013
Validation of the cephalosporin intradermal skin test for predicting immediate hypersensitivity: a prospective study with drug challenge
Cephalosporin is a major offending agent in terms of drug hypersensitivity along with penicillin. Cephalosporin intradermal skin… 
2007
2007
Ceftezole, a cephem antibiotic, is an α-glucosidase inhibitor with in vivo anti-diabetic activity
Using a high throughput-compatible assay to screen for potential alpha-glucosidase inhibitors, we found that the beta-lactam… 
Highly Cited
1995
Highly Cited
1995
Relationship between structure and convulsant properties of some beta-lactam antibiotics following intracerebroventricular microinjection in rats
The epileptogenic activities of several beta-lactam antibiotics were compared following their intracerebroventricular… 
1989
1989
Epileptogenic activity of some β-lactam derivatives: Structure-activity relationship
1988
1988
Mechanism of action of cephalosporins and resistance caused by decreased affinity for penicillin-binding proteins in Bacteroides fragilis
The susceptibilities of 52 clinical isolates of Bacteroides fragilis to five monoanionic cephalosporins were examined… 
1983
1983
Epileptogenic Activity of Cephalosporins in Rats and Their Structure‐Activity Relationship
Summary: The epileptogenic properties of 10 cephalosporins and penicillin G were compared by intraventricular application to rats… 
Review
1980
Review
1980
Medicinal chemistry of tetrazoles.
1976
1976
In Vitro and In Vivo Evaluation of Ceftezole, a New Cephalosporin Derivative
Ceftezole, a new cephalosporin derivative, was compared with cefazolin, cephaloridine, and cephalothin. Data obtained indicate… 
1976
1976
Ceftezole, a new cephalosporin C derivative I. In vitro and in vivo antimicrobial activity.
Ceftezole, a new cephalosporin antibiotic similar to cefazolin, has the following chemical structure: (6R,7R)-8-oxo-7[2-(1H… 
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