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ceftezole
Known as:
(6R,7R)-8-Oxo-7-(2-(1H-tetrazol-1-yl)acetamido)-3-((1,3,4-thiadiazol-2-ylthio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid
, Ceftezol
, demethylcefazolin
A semisynthetic first-generation cephalosporin with antibacterial activity. Ceftezole binds to and inactivates penicillin-binding proteins (PBPs…
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National Institutes of Health
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Related topics
Related topics
6 relations
Broader (2)
Anti-Bacterial Agents
Cefazolin
Narrower (3)
Celoslin
Falomesin
ceftezole sodium
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
A gold immunochromatographic assay for the rapid and simultaneous detection of fifteen β-lactams.
Yanni Chen
,
Yongwei Wang
,
+5 authors
Chuanlai Xu
Nanoscale
2015
Corpus ID: 205981343
A novel gold immunochromatographic assay (GICA) based on anti-β-lactam receptors was innovatively developed that successfully…
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Highly Cited
2013
Highly Cited
2013
Validation of the cephalosporin intradermal skin test for predicting immediate hypersensitivity: a prospective study with drug challenge
S. Yoon
,
S. Y. Park
,
+6 authors
T-B Kim
Allergy. European Journal of Allergy and Clinical…
2013
Corpus ID: 25316548
Cephalosporin is a major offending agent in terms of drug hypersensitivity along with penicillin. Cephalosporin intradermal skin…
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2007
2007
Ceftezole, a cephem antibiotic, is an α-glucosidase inhibitor with in vivo anti-diabetic activity
Dong-Sun Lee
,
Jin-Man Lee
,
Sung-Uk Kim
,
Kyu-Tae Chang
,
Sang-Han Lee
2007
Corpus ID: 59936951
Using a high throughput-compatible assay to screen for potential alpha-glucosidase inhibitors, we found that the beta-lactam…
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Highly Cited
1995
Highly Cited
1995
Relationship between structure and convulsant properties of some beta-lactam antibiotics following intracerebroventricular microinjection in rats
A. De Sarro
,
D. Ammendola
,
M. Zappalà
,
S. Grasso
,
G. De Sarro
Antimicrobial Agents and Chemotherapy
1995
Corpus ID: 5880843
The epileptogenic activities of several beta-lactam antibiotics were compared following their intracerebroventricular…
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1989
1989
Epileptogenic activity of some β-lactam derivatives: Structure-activity relationship
A. Sarro
,
G. Sarro
,
C. Ascioti
,
G. Nisticó
Neuropharmacology
1989
Corpus ID: 45966326
1988
1988
Mechanism of action of cephalosporins and resistance caused by decreased affinity for penicillin-binding proteins in Bacteroides fragilis
A. Yotsuji
,
J. Mitsuyama
,
+4 authors
S. Mitsuhashi
Antimicrobial Agents and Chemotherapy
1988
Corpus ID: 1621762
The susceptibilities of 52 clinical isolates of Bacteroides fragilis to five monoanionic cephalosporins were examined…
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1983
1983
Epileptogenic Activity of Cephalosporins in Rats and Their Structure‐Activity Relationship
C. Kamei
,
A. Sunami
,
K. Tasaka
Epilepsia
1983
Corpus ID: 33032789
Summary: The epileptogenic properties of 10 cephalosporins and penicillin G were compared by intraventricular application to rats…
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Review
1980
Review
1980
Medicinal chemistry of tetrazoles.
H. Singh
,
A. S. Chawla
,
V. Kapoor
,
D. Paul
,
R. Malhotra
Progress in Medicinal Chemistry
1980
Corpus ID: 38669754
1976
1976
In Vitro and In Vivo Evaluation of Ceftezole, a New Cephalosporin Derivative
M. Nishida
,
T. Murakawa
,
+6 authors
K. Miki
Antimicrobial Agents and Chemotherapy
1976
Corpus ID: 24225876
Ceftezole, a new cephalosporin derivative, was compared with cefazolin, cephaloridine, and cephalothin. Data obtained indicate…
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1976
1976
Ceftezole, a new cephalosporin C derivative I. In vitro and in vivo antimicrobial activity.
T. Noto
,
T. Nehashi
,
H. Endo
,
M. Saito
,
S. Matsubara
Journal of antibiotics (Tokyo. )
1976
Corpus ID: 27579996
Ceftezole, a new cephalosporin antibiotic similar to cefazolin, has the following chemical structure: (6R,7R)-8-oxo-7[2-(1H…
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