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ceftezole

Known as: (6R,7R)-8-Oxo-7-(2-(1H-tetrazol-1-yl)acetamido)-3-((1,3,4-thiadiazol-2-ylthio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, Ceftezol, demethylcefazolin 
A semisynthetic first-generation cephalosporin with antibacterial activity. Ceftezole binds to and inactivates penicillin-binding proteins (PBPs… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (2)

Anti-Bacterial AgentsCefazolin

Narrower (3)

CeloslinFalomesinceftezole sodium
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Ceftezole, a cephem antibiotic, is an α-glucosidase inhibitor with in vivo anti-diabetic activity
Using a high throughput-compatible assay to screen for potential alpha-glucosidase inhibitors, we found that the beta-lactam… 
1990
1990
Influences of cephem antibiotics on the immune response in mice.
The effects of six cephem antibiotics, including ceftezole, cefmetazole, cefoxitin, cefotiam, cefoperazone, and cefotaxime, on… 
1984
1984
Epileptogenic activity induced by intravenous injection of certain cephalosporins in rats.
Epileptogenic activity induced by intravenous injection of certain cephalosporin derivatives was studied. Ceftezole provided the… 
1983
1983
Epileptogenic Activity of Cephalosporins in Rats and Their Structure‐Activity Relationship
Summary: The epileptogenic properties of 10 cephalosporins and penicillin G were compared by intraventricular application to rats… 
1980
1980
Pharmacokinetics of ceftezole in patients with normal and impaired renal function.
The pharmacokinetics of ceftezole, a new cephalosporin antibiotic, was studied in 15 patients with normal and impaired renal… 
1976
1976
In Vitro and In Vivo Evaluation of Ceftezole, a New Cephalosporin Derivative
Ceftezole, a new cephalosporin derivative, was compared with cefazolin, cephaloridine, and cephalothin. Data obtained indicate… 
1976
1976
Ceftezole, a new cephalosporin C derivative I. In vitro and in vivo antimicrobial activity.
Ceftezole, a new cephalosporin antibiotic similar to cefazolin, has the following chemical structure: (6R,7R)-8-oxo-7[2-(1H… 
1976
1976
Ceftezole, a new cephalosporin C derivative II. Distribution and excretion in parenteral administration.
The distribution of ceftezole in blood and tissues and its excretion after intramuscular or intravenous administration of single… 
1976
1976
[Distribution and changes of antibiotic susceptibility of genus Haemophilus (author's transl)].
We studied on the distribution and changes of antibiotic susceptibility of H. influenzae, H. parainfluenzae and H… 
1976
1976
Ocular Penetration and Clinical Evaluation of Ceftezole for Ocular Infections
Intraocular penetration of Ceftezole (CTZ) was investigated in rabbit eye. The peak of aqueous humor level, 1.36 ug/ml, attained… 
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