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cefroxadine

Known as: 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((amino-1,4-cyclohexadien-1-ylacetyl)amino)-3-methoxy-8-oxo-, (6R-(6 alpha,7 beta(R*)))-, 7-(D-2-amino-2-(1,4-cyclohexadienyl)acetamido)-3-methoxy-3-cephem-4-carboxylic acid, cefroxadin 
A semisynthetic first-generation cephalosporin with antibacterial activity. Cefroxadine binds to and inactivates penicillin-binding proteins (PBPs… 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

CGP 9000

Broader (1)

Cephradine
analogs & derivatives

Papers overview

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2003
2003
Inhibition of in vitro intestinal absorption of D-galactose by cefroxadine, cefatrizine and cefaloglycin
Objective: To investigate the effect of the three aminocephalosporin antibiotics, cefroxadine, cefatrizine, and cephaloglycin on… 
1986
1986
[Influence of cefroxadine dry syrup on intestinal bacterial flora].
Influence of cefroxadine (CXD) dry syrup on intestinal bacterial flora was studied in mice infected with 4 species of bacteria… 
1983
1983
Relationship between pharmacokinetics and bioavailability of cefroxadine (CGP 9000) and renal function.
The pharmacokinetics and bioavailability of cefroxadine were studied in 15 patients with different renal functions after… 
1983
1983
[Double-blind comparative trial of cefroxadine and cephalexin in the treatment of acute suppurative otitis media and acute exacerbation of chronic suppurative otitis media].
A double-blind controlled trial of cefroxadine (CXD) 250 mg t.i.d. was undertaken to objectively evaluate its safety and… 
1983
1983
[Comparative double-blind study of cefroxadine and cephalexin in the treatment of complicated urinary tract infection].
To evaluate the efficacy, safety, and utility of cefroxadine (CXD) for the treatment of complicated urinary tract infections, a… 
1982
1982
Solvent drag effect in drug intestinal absorption. I. Studies on drug and D2O absorption clearances.
It was shown that the intestinal absorption clearance of D2O (CLD2O) could be a more appropriate index to study the solvent drag… 
1981
1981
Pharmacokinetics of cefroxadine in healthy volunteers and patients with impaired renal function.
The pharmacokinetics of cefroxadine, a new orally active broad-spectrum cephalosporin, was studied in healthy volunteers and… 
1981
1981
[Laboratory and clinical studies of cefroxadine (author's transl)].
The authors have carried out the laboratory and clinical studies of cefroxadine (CXD), and obtained the following results. The… 
1981
1981
Comparison of microbiological and high pressure liquid chromatographic assays of the new cephalosporin cefroxadine.
A method employing high pressure liquid chromatography has been developed for the new cephalosporin cefroxadine (CGP 9000). This… 
1980
1980
Pharmacokinetics of a new cephalosporin, CGP 9000 (cefroxadine), in healthy volunteers.
Oral doses of 125, 250, and 500 mg of a new cephalosporin, CGP 9000 (7 beta-[D-2-amino-2-(1,4-cyclohexadienyl)-acetamido]-3…