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cefroxadine

Known as: 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((amino-1,4-cyclohexadien-1-ylacetyl)amino)-3-methoxy-8-oxo-, (6R-(6 alpha,7 beta(R*)))-, 7-(D-2-amino-2-(1,4-cyclohexadienyl)acetamido)-3-methoxy-3-cephem-4-carboxylic acid, cefroxadin 
A semisynthetic first-generation cephalosporin with antibacterial activity. Cefroxadine binds to and inactivates penicillin-binding proteins (PBPs… 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

CGP 9000

Broader (1)

Cephradine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Penicillins, cephalosporins, other beta-lactam antibiotics, and tetracyclines
1997
1997
Inhibitory effects of angiotensin-converting enzyme inhibitor on cefroxadine uptake by rabbit small intestinal brush border membrane vesicles.
Effects of angiotensin-converting enzyme (ACE) inhibitors, captopril, enalapril maleate and quinapril, on the uptake of… 
1988
1988
Microbore liquid chromatographic determination of cadralazine and cephalexin in plasma with large-volume injection.
Highly Cited
1983
Highly Cited
1983
Characterization of aminocephalosporin transport across rat small intestine.
The absorption mechanism of aminocephalosporins was investigated in rat small intestine. Cephalosporins chosen in this study were… 
Highly Cited
1982
Highly Cited
1982
Determination of cefsulodin, cefotiam, cephalexin, cefotaxime, desacetyl-cefotaxime, cefuroxime and cefroxadin in plasma and urine by high-performance liquid chromatography.
1982
1982
Pharmacokinetics of cefroxadin (CGP 9000) in man
The pharmacokinetics of cefroxadin have been studied after the administration of single oral and intravenous doses to healthy… 
1982
1982
Antibacterial effects of cefroxadine, cephalexin and cephradine in a new in vitro pharmacokinetic model.
A pharmacokinetic model has been developed, by means of which all possible time courses of the concentrations of antibiotics in… 
1982
1982
Solvent drag effect in drug intestinal absorption. I. Studies on drug and D2O absorption clearances.
It was shown that the intestinal absorption clearance of D2O (CLD2O) could be a more appropriate index to study the solvent drag… 
1980
1980
Pharmacokinetics of a new cephalosporin, CGP 9000 (cefroxadine), in healthy volunteers.
Oral doses of 125, 250, and 500 mg of a new cephalosporin, CGP 9000 (7 beta-[D-2-amino-2-(1,4-cyclohexadienyl)-acetamido]-3… 
1980
1980
Cefroxadine (CGP-9000), an orally active cephalosporin
Cefroxadine (GCP-9000; CXD), 7 beta[D-2-amino-2-(1,4-cyclohexadienyl)-acetamido]-3-methoxy-ceph-3-em-carboxylic acid, is a new… 
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