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cefbuperazone

Known as: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((2-(((4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)-3-hydroxy-1-oxobutyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, (6R-(6alpha,7alpha,7(2R*,3S*)))- 
A semisynthetic second-generation cephalosporin with antibacterial activity. Cefbuperazone binds to and inactivates penicillin-binding proteins (PBPs… 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

BMY-25182T 1982
Cefbuperazone Sodium

Broader (1)

Cephamycins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1990
1990
Paradoxical activity of beta-lactam antibiotics against Proteus vulgaris in experimental infection in mice
In previous papers (Y. Ikeda and T. Nishino, Antimicrob. Agents Chemother. 32:1073-1077, 1988; Y. Ikeda, T. Nishino, and T… 
1988
1988
European collaborative study of reproducibility of quantitative sensitivity testing of anaerobes.
Minimum inhibitory concentrations (MICs) of ampicillin, cefoxitin, cefbuperazone, latamoxef, metronidazole, clindamycin and… 
1987
1987
Testicular toxicity of N-methyltetrazolethiol cephalosporin analogs in the juvenile rat.
1985
1985
In vitro activity of cefbuperazone against anaerobic bacteria
The in vitro activity of cefbuperazone was compared with that of cefoxitin, moxalactam, and piperacillin against 305 strains of… 
1985
1985
In vitro activity of cefbuperazone and other antimicrobial agents against isolates from the female genital tract
Cefbuperazone (BMY 25182), a new cephamycin, showed activity similar to those of moxalactam and other cephalosporin-cephamycins… 
1985
1985
In vivo activity of cefbuperazone (T-1982) against various experimental infections in mice.
The protective activity of cefbuperazone (T-1982) was compared with those of latamoxef, cefotaxime, and cefmetazole against… 
1985
1985
In vitro activity of cefbuperazone compared with that of other new beta-lactam agents against anaerobic gram-negative bacilli and contribution of beta-lactamase to resistance
Cefbuperazone was compared with other currently available and investigational antibiotics against 278 clinical isolates of… 
1985
1985
Comparative in vitro activity of cefbuperazone against anaerobic bacteria isolated from community hospitals
The activity of cefbuperazone against 266 strains of anaerobic bacteria was determined by the agar dilution method and compared… 
1985
1985
In vitro activity of cefbuperazone, a new cephamycin, against anaerobic bacteria
The 90% MIC of cefbuperazone (BMY 25182) was 32 micrograms/ml for Bacteroides fragilis and Bacteroides spp., 128 micrograms/ml… 
1985
1985
In vitro activity of Sch 34343 and cefbuperazone against anaerobic bacteria
The in vitro activities of Sch 34343, a new penem antibiotic, and cefbuperazone, a new cephamycin antibiotic, were determined… 
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