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cefbuperazone

Known as: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((2-(((4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)-3-hydroxy-1-oxobutyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, (6R-(6alpha,7alpha,7(2R*,3S*)))- 
A semisynthetic second-generation cephalosporin with antibacterial activity. Cefbuperazone binds to and inactivates penicillin-binding proteins (PBPs… 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

BMY-25182T 1982
Cefbuperazone Sodium

Broader (1)

Cephamycins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1990
1990
Pharmacokinetics of cephem antibiotics in exudate of pelvic retroperitoneal space after radical hysterectomy and pelvic lymphadenectomy
Many cephalosporin antibiotics have recently been invented and attempts have been made to use them clinically. The choice of… 
1988
1988
European collaborative study of reproducibility of quantitative sensitivity testing of anaerobes.
Minimum inhibitory concentrations (MICs) of ampicillin, cefoxitin, cefbuperazone, latamoxef, metronidazole, clindamycin and… 
1987
1987
Paradoxical antibacterial activity of cefmenoxime against Proteus vulgaris
The growth-inhibitory effect of cefmenoxime against Proteus vulgaris was studied by using the broth dilution and paper disk… 
1986
1986
[In vivo antibacterial activity of cefbuperazone. Synergy of cefbuperazone for bactericidal effect with human polymorphonuclear leukocytes].
Studies were done utilizing E. coli No. 59 which are resistant against human and mouse serum, and the following results were… 
1985
1985
In vitro activity of cefbuperazone against anaerobic bacteria
The in vitro activity of cefbuperazone was compared with that of cefoxitin, moxalactam, and piperacillin against 305 strains of… 
1985
1985
In vitro activity of cefbuperazone compared with that of other new beta-lactam agents against anaerobic gram-negative bacilli and contribution of beta-lactamase to resistance
Cefbuperazone was compared with other currently available and investigational antibiotics against 278 clinical isolates of… 
1985
1985
In vivo activity of cefbuperazone (T-1982) against various experimental infections in mice.
The protective activity of cefbuperazone (T-1982) was compared with those of latamoxef, cefotaxime, and cefmetazole against… 
1985
1985
Comparative in vitro activity of cefbuperazone against anaerobic bacteria isolated from community hospitals
The activity of cefbuperazone against 266 strains of anaerobic bacteria was determined by the agar dilution method and compared… 
1985
1985
In vitro activity of cefbuperazone, a new cephamycin, against anaerobic bacteria
The 90% MIC of cefbuperazone (BMY 25182) was 32 micrograms/ml for Bacteroides fragilis and Bacteroides spp., 128 micrograms/ml… 
1984
1984
[Pharmacokinetic studies of cefbuperazone in the field of gynecology].
Cefbuperazone (CBPZ), a new cephamycin antibiotic, was studied for the distribution in the genital organs and the excretion to… 
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