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cefazaflur

Known as: (6R,7R)-3-(((1-Methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-7-(2-((trifluormethyl)thio)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure, 7-trifluoromethylthioacetamido-3-(1-methyl-lH- tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid 
A semisynthetic first-generation cephalosporin with antibacterial activity. Cefazaflur binds to and inactivates penicillin-binding proteins (PBPs… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Cephalosporins

Narrower (1)

SK&F 59962

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
SU-G-JeP2-04: Comparison Between Fricke-Type 3D Radiochromic Dosimeters for Real-Time Dose Distribution Measurements in MR-Guided Radiation Therapy.
PURPOSE To assess MR signal contrast for different ferrous ion compounds used in Fricke-type gel dosimeters for real-time dose… 
2005
2005
Beta lactamase resistance of newer cephalosporins and antimicrobial effectiveness against gram-negative bacilli
SummaryThree newer cephalosporins (cefamandole, cefoxitin and cefazaflur) were investigated, in comparison with three older… 
1981
1981
Die Rolle der Prostaglandine in der Reproduktion: Mögliche Mitwirkung bei der Ovulation
In allen bislang untersuchten Saugetierarten geht der Ovulation eine hypophysare LH- (und FSH-)Aussehuttung voraus, verursacht… 
1978
1978
Use of a Heavy Inoculum in the In Vitro Evaluation of the Anti-Staphylococcal Activity of 19 Cephalosporins
The in vitro activity of 19 cephalosporins against 105 clinical isolates of Staphylococcus aureus and S. epidermidis was… 
1978
1978
Semiautomated turbidimetric microbiological assay for cefazaflur.
A quantitative semi-automated turbidimetric bioassay for cefazaflur, using Streptococcus faecium as the indicator, is described… 
1977
1977
In vitro studies with cefazaflur and other parenteral cephalosporins.
Cefazaflur has a broad-spectrum of in vitro antibacterial activity equal to or greater than that of the commercially-available… 
1977
1977
Pharmacokinetic Study of Cefazaflur Compared to Cephalothin and Cefazolin
A single 1-Gm dose of cefazaflur, a new semisynthetic cephalosporin derivative, was compared in a crossover study to the same… 
1977
1977
Cefazaflur, aNewParenteral Cephalosporin: InVitro Studies
Cefazaflur was tested invitro against 262strains ofbacteria. Inhibitory and bactericidal concentrations were determined… 
1977
1977
Cefuroxime Resistance to Staphylococcal β-Lactamases
Materials and Methods The 35 S. aureus organisms studied were all from clinical isolates described in a recent publication… 
1976
1976
Synthesis and in vitro antibacterial activity of 7-trifluoromethylthioacetamido cephamycins related to SK&F 59962 (cefazaflur).
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