Skip to search form
Skip to main content
>
Semantic Scholar
Semantic Scholar's Logo
Search
Sign In
Create Free Account
You are currently offline. Some features of the site may not work correctly.
catechol O-methyltransferase activity
Known as:
S-COMT (soluble form of catechol-O-methyltransferase)
, COMT II
, catechol methyltransferase activity
Expand
Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol. [EC:2.1.1.6]
National Institutes of Health
Create Alert
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Catechol-O-Methyltransferase Valine158Methionine Polymorphism Moderates Methylphenidate Effects on Oppositional Symptoms in Boys with Attention-Deficit/Hyperactivity Disorder
A. Salatino-Oliveira
,
J. Genro
,
C. Zeni
,
G. Polanczyk
,
M. Hutz
Biological Psychiatry
2011
Corpus ID: 22061875
BACKGROUND The catechol-O-methyltransferase enzyme plays a key role in the function of prefrontal cortex, accounting for most of…
Expand
2011
2011
Association study of a functional catechol-o-methyltransferase polymorphism and cognitive function in patients with dementia.
G. Nedić
,
F. Borovečki
,
+5 authors
N. Pivac
Collegium antropologicum
2011
Corpus ID: 1216948
A functional catechol-o-methyltransferase (COMT Val158/108Met) polymorphism, a valine (Val) to methionine (Met) substitution, has…
Expand
2010
2010
Association of COMT haplotypes and breast cancer risk in caucasian women.
N. Peterson
,
A. Trentham-Dietz
,
+6 authors
K. Egan
Anticancer research
2010
Corpus ID: 5930196
Catechol-O-methyl transferase (COMT) is an important estrogen-metabolizing enzyme, and common genetic variants in this gene could…
Expand
Highly Cited
2009
Highly Cited
2009
Association between dopaminergic polymorphisms and borderline personality traits among at-risk young adults and psychiatric inpatients
Z. Nemoda
,
K. Lyons-Ruth
,
A. Székely
,
Eszter Bertha
,
G. Faludi
,
M. Sasvári-Székely
Behavioral and Brain Functions
2009
Corpus ID: 2885132
BackgroundIn the development of borderline personality disorder (BPD) both genetic and environmental factors have important roles…
Expand
2006
2006
Analysis of functional polymorphisms in three synaptic plasticity-related genes (BDNF, COMT AND UCHL1) in Alzheimer's disease in Colombia
D. Forero
,
B. Benitez
,
G. Arboleda
,
J. Yunis
,
H. Arboleda
Neuroscience Research
2006
Corpus ID: 33692423
In recent years, it has been proposed that synaptic dysfunction may be an important etiological factor for Alzheimer's disease…
Expand
2004
2004
Structure of the tobacco caffeic acid O-methyltransferase (COMT) II gene: identification of promoter sequences involved in gene inducibility by various stimuli
Valérie Toquin
,
B. Grausem
,
P. Geoffroy
,
M. Legrand
Plant Molecular Biology
2004
Corpus ID: 12757195
The tobacco gene encoding caffeic acid-O-methyltransferase of class II (COMT II) was isolated, including a 1.7 kb 5′-flanking…
Expand
2001
2001
l-Dopa Upregulates the Expression and Activities of Methionine Adenosyl Transferase and Catechol-O-Methyltransferase
W. Zhao
,
L. Latinwo
,
Xiao-xiao Liu
,
E. Lee
,
C. Charlton
Experimental Neurology
2001
Corpus ID: 6988887
High nonphysiological doses of l-dopa are administered to Parkinson's disease (PD) patients, to replenish the depleted dopamine…
Expand
2000
2000
Substrate preferences of caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferases in developing stems of alfalfa (Medicago sativa L.).
K. Inoue
,
K. Parvathi
,
R. A. Dixon
Archives of biochemistry and biophysics
2000
Corpus ID: 41904159
Caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase (COMT, EC 1.2.1.68) catalyzes at least two reactions in lignin…
Expand
Highly Cited
1999
Highly Cited
1999
Tobacco O-methyltransferases involved in phenylpropanoid metabolism. The different caffeoyl-coenzyme A/5-hydroxyferuloyl-coenzyme A 3/5-O-methyltransferase and caffeic acid/5-hydroxyferulic acid 3/5…
S. Maury
,
P. Geoffroy
,
M. Legrand
Plant physiology
1999
Corpus ID: 23330308
The biosynthesis of lignin monomers involves two methylation steps catalyzed by orthodiphenol-O-methyltransferases: caffeic acid…
Expand
1979
1979
Multiple molecular forms of catechol-O-methyltransferase. Evidence for two distinct forms, and their purification and physical characterization.
M. Huh
,
A. Friedhoff
The Journal of biological chemistry
1979
Corpus ID: 34259594
Catechol-O-methyltransferase (COMT: EC 2.1.1.6) has been shown to exist in the soluble fraction of rat liver as two distinct…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
,
Terms of Service
, and
Dataset License
ACCEPT & CONTINUE