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castanospermine

Known as: 1,6,7,8-tetrahydroxyoctahydroindolizine, castinospermine 
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (3)

1-epicastanospermine6,7-diepicastanospermine6-epicastanospermine

Broader (8)

AlkaloidsAnti-HIV AgentsAnti-Inflammatory Agents, Non-SteroidalAntiviral Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Tunicamycin inhibits Toll-like receptor-activated inflammation in RAW264.7 cells by suppression of NF-κB and c-Jun activity via a mechanism that is independent of ER-stress and N-glycosylation.
2005
2005
Novel synthesis of castanospermine and 1-epicastanospermine.
[reaction: see text] Polyhydroxylated indolizidines have potential for treatment of HIV, hepatitis C and HSV infection, multiple… 
2003
2003
The cargo receptor ERGIC-53 is a target of the unfolded protein response.
2002
2002
Castanospermine-trehazolin hybrids: a new family of glycomimetics with tuneable glycosidase inhibitory properties.
Bicyclic azasugar glycomimetics related to castanospermine and trehazolin have been prepared from sugar carbodiimides via… 
Highly Cited
2001
Highly Cited
2001
Intermolecular Michael addition of substituted amines to a sugar-derived alpha,beta-unsaturated ester: synthesis of 1-deoxy-D-gluco- and -L-ido-homonojirimycin, 1-deoxy-castanospermine and 1-deoxy-8a…
The synthesis of polyhydroxylated piperidine alkaloids, namely, 1-deoxy-D-gluco-homonojirimycin 3a, 1-deoxy-L-ido-homonojirimycin… 
1995
1995
Processing and transport of a lysosomal membrane glycoprotein is developmentally regulated in African trypanosomes.
1992
1992
Nonselective utilization of the endomannosidase pathway for processing glycoproteins by human hepatoma (HepG2) cells.
Highly Cited
1990
Highly Cited
1990
Demonstration that Golgi endo-alpha-D-mannosidase provides a glucosidase-independent pathway for the formation of complex N-linked oligosaccharides of glycoproteins.
1988
1988
Assembly of asparagine-linked oligosaccharides in baby hamster kidney cells treated with castanospermine, an inhibitor of processing glucosidases.
We have shown previously that the processing of asparagine-linked oligosaccharides in baby hamster kidney (BHK) cells is blocked… 
Highly Cited
1988
Highly Cited
1988
Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1.
Human immunodeficiency virus type 1 (HIV-1), the retrovirus responsible for acquired immunodeficiency syndrome (AIDS), contains… 
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