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carnitine biosynthetic process

Known as: vitamin Bt biosynthetic process, carnitine synthesis, carnitine formation 
The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in… 
National Institutes of Health

Papers overview

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1996
1996
Inhibition of carnitine biosynthesis by valproic acid in rats--the biochemical mechanism of inhibition.
Highly Cited
1995
Highly Cited
1995
Canine hereditary ceroid-lipofuscinosis: evidence for a defect in the carnitine biosynthetic pathway.
The ceroid-lipofuscinoses are a group of autosomal-recessive hereditary lysosomal storage diseases that have been characterized… 
Highly Cited
1989
Highly Cited
1989
Utilization of dietary precursors for carnitine synthesis in human adults.
Endogenous synthetic pathways are presumed to be sufficient to provide adequate amounts of carnitine to meet the needs of the… 
1985
1985
Carnitine levels in iron-deficient rat pups.
Hypertriglyceridemia and fatty livers have been observed in pups of Fe-deficient rats. Lowered tissue carnitine level is proposed… 
Highly Cited
1984
Highly Cited
1984
Carnitine biosynthesis from gamma-butyrobetaine and from exogenous protein-bound 6-N-trimethyl-L-lysine by the perfused guinea pig liver. Effect of ascorbate deficiency on the in situ activity of…
The production of carnitine from peptide-bound 6-N-trimethyl-L-lysine (Lys(Me3)) or 4-N-trimethyl-aminobutyrate(gamma… 
Highly Cited
1977
Highly Cited
1977
Carnitine deficiency: clinical, morphological, and biochemical observations in a fatal case.
A fatal case of carnitine deficiency is described. The patient had intermittent metabolic acidosis, fluctuating hepatomegaly, and… 
1977
1977
Biosynthesis of carnitine in Neurospora crassa.
1977
1977
Lysine deficiency and carnitine in male and female rats.
This study continues investigations from this laboratory on the question of the severity of carnitine deficiency in rats fed a 20… 
Highly Cited
1974
Highly Cited
1974
Carnitine and trimethylaminobutyrate synthesis in rat tissues.
Liver and testis slices convert 6-N-trimethyl-lysine into 4-N-trimethylaminobutyrate and carnitine. Adipose, skeletal muscle… 
Highly Cited
1962
Highly Cited
1962
Carnitine precursors in the rat.
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