carnitine biosynthetic process

Known as: vitamin Bt biosynthetic process, carnitine synthesis, carnitine formation 
The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in… (More)
National Institutes of Health

Papers overview

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2009
2009
Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation.
Peroxisome proliferator-activated receptor-alpha (PPARalpha) is a master transcriptional regulator of beta-oxidation and a… (More)
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2006
2006
PPARalpha agonists up-regulate organic cation transporters in rat liver cells.
It has been shown that clofibrate treatment increases the carnitine concentration in the liver of rats. However, the molecular… (More)
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2005
2005
Characterization of carnitine and fatty acid metabolism in the long-chain acyl-CoA dehydrogenase-deficient mouse.
In the present paper, we describe a novel method which enables the analysis of tissue acylcarnitines and carnitine biosynthesis… (More)
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Review
2004
Review
2004
Carnitine: a nutritional, biosynthetic, and functional perspective.
Carnitine status in humans is reported to vary according to body composition, gender, and diet. Plasma carnitine concentration… (More)
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Review
2003
Review
2003
Carnitine and hemodialysis.
Carnitine, gamma-trimethyl-beta-hydroxybutyrobetaine, is a small molecule widely present in all cells from prokaryotic to… (More)
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Review
2003
Review
2003
Carnitine metabolism and deficit--when supplementation is necessary?
Carnitine is an ammo acid derivative found in high energy demanding tissues (skeletal muscles, myocardium, the liver and the… (More)
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Review
1991
Review
1991
Ascorbic acid and carnitine biosynthesis.
It has been suggested that early features of scurvy (fatigue and weakness) may be attributed to carnitine deficiency. Ascorbate… (More)
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1978
1978
Carnitine biosynthesis. beta-Hydroxylation of trimethyllysine by an alpha-ketoglutarate-dependent mitochondrial dioxygenase.
Rat liver mitochondria were found to hydroxylate epsilon-N-trimethyl-L-lysine to produce beta-hydroxy-epsilon-N-trimethyl-L… (More)
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1977
1977
Deficiency of carnitine in cachectic cirrhotic patients.
Carnitine is synthesized from lysine and methionine. In the rat, inadequate intake of either of these essential amino acids… (More)
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Highly Cited
1963
Highly Cited
1963
LONG-CHAIN CARNITINE ACYLTRANSFERASE AND THE ROLE OF ACYLCARNITINE DERIVATIVES IN THE CATALYTIC INCREASE OF FATTY ACID OXIDATION INDUCED BY CARNITINE.
Carnitine-H3 or palmitate-U4 incubated with heart muscle preparations waa incorporated into a compound that had chromatographic… (More)
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