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cardiolipin metabolic process

Known as: cardiolipin metabolism 
The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol. [CHEBI:28494, GOC:mah]
National Institutes of Health

Related topics

Related topics

2 relations
negative regulation of cardiolipin metabolic processpositive regulation of cardiolipin metabolic process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
The effects of chronic muscle use and disuse on cardiolipin metabolism.
Cardiolipin (CL) is a phospholipid that maintains the integrity of mitochondrial membranes. We previously demonstrated that CL… Expand
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2013
2013
Relationship between cardiolipin metabolism and oxygen availability in Bacillus subtilis☆
We report changes of the content of anionic phospholipids in Bacillus subtilis in response to hypoxic conditions and inhibition… Expand
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Highly Cited
2010
Highly Cited
2010
Dynamic simulation of cardiolipin remodeling: greasing the wheels for an interpretative approach to lipidomics[S]
Cardiolipin is a class of mitochondrial specific phospholipid, which is intricately involved in mitochondrial functionality… Expand
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Highly Cited
2009
Highly Cited
2009
Mitochondrial Cardiolipin Involved in Outer-Membrane Protein Biogenesis: Implications for Barth Syndrome
The biogenesis of mitochondria requires the import of a large number of proteins from the cytosol [1, 2]. Although numerous… Expand
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Highly Cited
2009
Highly Cited
2009
Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria
Cardiolipin, a unique phospholipid composed of four fatty acid chains, is located mainly in the mitochondrial inner membrane (IM… Expand
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Highly Cited
2006
Highly Cited
2006
The Enzymatic Function of Tafazzin*
Tafazzin is a putative enzyme that is involved in cardiolipin metabolism, it may carry mutations responsible for Barth syndrome… Expand
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Highly Cited
2005
Highly Cited
2005
Shotgun lipidomics identifies cardiolipin depletion in diabetic myocardium linking altered substrate utilization with mitochondrial dysfunction.
Diabetic cardiomyopathy is characterized by excessive utilization of fatty acid substrate, diminished glucose transport, and… Expand
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Highly Cited
2003
Highly Cited
2003
Aberrant cardiolipin metabolism in the yeast taz1 mutant: a model for Barth syndrome.
In eukaryotic cells, the acyl species of the phospholipid cardiolipin (CL) are more highly unsaturated than those of the other… Expand
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Highly Cited
2003
Highly Cited
2003
Only One Splice Variant of the Human TAZ Gene Encodes a Functional Protein with a Role in Cardiolipin Metabolism*
Barth syndrome (BTHS) is an X-linked recessive disorder caused by mutations in the TAZ gene and is characterized by… Expand
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Highly Cited
2000
Highly Cited
2000
Defective remodeling of cardiolipin and phosphatidylglycerol in Barth syndrome.
Cardiolipin (CL) and phosphatidylglycerol (PG) are the major polyglycerophospholipids observed in mammalian tissues. CL is… Expand
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