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carboxymethylproline synthase

National Institutes of Health

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Broader (1)

Carbon-Carbon Lyases

Papers overview

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Review
2009
Review
2009
Evidence that Thienamycin Biosynthesis Proceeds via C‐5 Epimerization: ThnE Catalyzes the Formation of (2S,5S)‐trans‐Carboxymethylproline
The biosynthetic pathways leading to most clinically important families of bicyclic b-lactam antibiotics and b-lactamase… 
2005
2005
Structural and Mechanistic Studies on Carboxymethylproline Synthase (CarB), a Unique Member of the Crotonase Superfamily Catalyzing the First Step in Carbapenem Biosynthesis*
The first step in the biosynthesis of the medicinally important carbapenem family of β-lactam antibiotics is catalyzed by… 
2005
2005
Synthesis of deuterium labelled L- and D-glutamate semialdehydes and their evaluation as substrates for carboxymethylproline synthase (CarB)--implications for carbapenem biosynthesis.
Carboxymethylproline synthase was shown to condense L-glutamate semialdehyde with malonyl-coenzyme A to produce (2S,5S… 
2004
2004
Carboxymethylproline Synthase (CarB), an Unusual Carbon-Carbon Bond-forming Enzyme of the Crotonase Superfamily Involved in Carbapenem Biosynthesis*
Carboxymethylproline synthase (CarB) catalyzes the committed step in the biosynthesis of (R)-1-carbapen-2-em-3-carboxylate, the… 
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