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carboxymefloquine

National Institutes of Health

Papers overview

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2014
2014
ABSTRACT Malaria patients are frequently coinfected with HIV and mycobacteria causing tuberculosis, which increases the use of… Expand
2014
2014
OBJECTIVES Mefloquine/artesunate has recently been developed as a fixed-dose combination, providing a promising rescue… Expand
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2009
2009
A method for the simultaneous analysis of the enantiomers of mefloquine (MQ) and its main metabolite carboxymefloquine (CMQ) in… Expand
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2007
2007
Increase in drug detoxification and alteration of drug uptake and efflux of Plasmodium falciparum were investigated for their… Expand
2005
2005
Plasmodium knowlesi (W1) shows a high level of innate resistance to mefloquine as shown by recrudescence of blood-induced… Expand
Highly Cited
2000
Highly Cited
2000
We studied mefloquine metabolism in cells and microsomes isolated from human and animal (monkey, dog, rat) livers. In both… Expand
1999
1999
An improved high-performance liquid chromatography method using a low silanol activity octadecylsilica column and a solid-phase… Expand
Highly Cited
1997
Highly Cited
1997
The pharmacokinetics of the enantiomers of mefloquine were studied in the rat after administration of a racemic mixture and of… Expand
Review
1994
Review
1994
Summary— Malaria remains a major public health problem in large areas of the world. One of the major factors responsible for the… Expand
1992
1992
A number of drugs have been studied for their effect on the metabolism of the antimalarial drug mefloquine by human liver… Expand