carbazeran
National Institutes of Health
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The PXB-mouse is potentially a useful in vivo model to predict human hepatic metabolism and clearance. Four model compounds, [14C…
Tamoxifen, raloxifene, and nafoxidine are selective estrogen receptor modulators (SERMs) reported to inhibit the catalytic…
The importance of aldehyde oxidase (AOX) is becoming increasingly recognized in the prediction of human pharmacokinetic…
Common marmosets (Callithrix jacchus), New World monkeys, are a promising primate model for preclinical drug metabolism studies…
1. After administration of [14C]-carbazeran by oral gavage to guinea pigs, 48% of the dosed radioactivity was recovered in urine…
Phosphodiesterase enzyme (PDE) inhibitors form a diverse category of chemical structures which display positive inotropic…