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carbamazepine epoxide
Known as:
10,11-epoxycarbamazepine
, Carbamazepine 10,11-Epoxide
, carbamazepine 10,11-oxide
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National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Carbamazepine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
A new herb-drug interaction of Polygonum cuspidatum, a resveratrol-rich nutraceutical, with carbamazepine in rats.
Y. Chi
,
Shiuan-Pey Lin
,
Yu-Chi Hou
Toxicology and Applied Pharmacology
2012
Corpus ID: 28310837
Highly Cited
2009
Highly Cited
2009
Carbamazepine: placental transport, tissue concentrations in foetus and newborn, and level in milk.
Seppo Pynnönen
,
Jussi Kanto
,
Matti Sillanpää
,
R. Erkkola
Acta Pharmacologica et Toxicologica
2009
Corpus ID: 13536544
The pharmacokinetics of carbamazepine were studied during pregnancy and early childhood by investigating the extent of its…
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2001
2001
Determination of carbamazepine and its metabolite carbamazepine-10,11-epoxide in serum with gas-chromatography mass spectrometry.
G. Minkova
,
D. Getova
Methods and Findings in Experimental and Clinical…
2001
Corpus ID: 42903660
Carbamazepine, one of the most often used antiepileptic drugs, undergoes enzyme biotransformation through epoxidation with the…
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Review
1999
Review
1999
A multiple‐dose safety and bioequivalence study of a narrow therapeutic index drug: A case for carbamazepine
A. Yacobi
,
S. Zlotnick
,
+7 authors
B. Levitt
Clinical pharmacology and therapy
1999
Corpus ID: 29474764
1998
1998
Microsomal metabolism of carbamazepine and oxcarbazepine in liver and placenta
P. Myllynen
,
P. Pienimäki
,
H. Raunio
,
K. Vähäkangas
Human and Experimental Toxicology
1998
Corpus ID: 24778655
Metabolism of both carbamazepine (CBZ) and oxcarbaze-pine (OCBZ) were catalyzed by human liver microsomes and microsomes from…
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1995
1995
Metabolism of carbamazepine and co-administered anticonvulsants during pregnancy
I. Bernus
,
W. Hooper
,
R. Dickinson
,
M. Eadie
Epilepsy Research
1995
Corpus ID: 231087
1990
1990
Interaction of Carbamazepine‐10,11‐Epoxide, an Active Metabolite of Carbamazepine, with Valproate: A Pharmacokinetic Study
Francesco Pisani
,
M. Caputo
,
+5 authors
L. Bertilsson
Epilepsia
1990
Corpus ID: 11016408
Summary: The mechanism responsible for the valproate (VPA)‐induced elevation of serum carbamazepine‐10,11‐epoxide (CBZ‐E) levels…
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Highly Cited
1987
Highly Cited
1987
Serum Concentrations of Carbamazepine and Its Epoxide and Diol Metabolites in Epileptic Patients: The Influence of Dose and Comedication
B. Rambeck
,
T. W. May
,
U. Juergens
Therapeutic Drug Monitoring
1987
Corpus ID: 11539348
The influence of carbamazepine (CBZ) dose, CBZ preparation used, comedication (phenobarbital, phenytoin, primidone, valproate…
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1978
1978
Brain concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients
M. Friis
,
J. Christiansen
,
E. Hvidberg
European Journal of Clinical Pharmacology
1978
Corpus ID: 10712833
SummaryCarbamazepine (CBZ) and carbamazepine-10,11-epoxide (CBZ-Epoxide) in the temporal lobe were measured in five epileptic…
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1976
1976
Effect of carbamazepine on cholinergic parameters in rat brain areas
S. Consolo
,
S. Bianchi
,
H. Ladinsky
Neuropharmacology
1976
Corpus ID: 39934154
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