caracemide

Known as: Acetamide, N-[(Methylamino)carbonyl]-N-[[(methylamino)carbonyl]oxy]-(9CI), Acetamide, N-[(methylamino)carbonyl]-N-[[(methylamino)carbonyl]oxy]- (9CI), N-Acetyl-N-(methylcarbamoyloxy)-N'-methylurea 
An agent derived from acetohydroxamic acid with potential antineoplastic activity. Caracemide inhibits ribonuclease reductase, resulting in decreased… (More)

Topic mentions per year

Topic mentions per year

1984-2014
012319842014

Papers overview

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1999
1999
Twenty-four previously untreated, ambulatory patients with advanced colorectal carcinoma were treated with either caracemide (11… (More)
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1996
1996
Forty-eight previously untreated, ambulatory patients with advanced or unresectable renal carcinoma were treated with either… (More)
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1992
1992
Caracemide (NacetylN(methylcarbamoyloxy)N-methylurea) is a nonspecific inhibitor of macromolecular synthesis [1]. It has in vitro… (More)
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1992
1992
The anticancer drug caracemide, N-acetyl-N,O- di(methylcarbamoyl)hydroxylamine, and one of its degradation products, N-acetyl-O… (More)
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1990
1990
The antitumor agent caracemide [N-acetyl-N-(methylcarbamoyloxy)-N'-methylurea] has been observed to induce signs of cholinergic… (More)
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1987
1987
We conducted a phase I trial of caracemide, a new chemotherapeutic agent, which is active in the MX1 (mammary) and CX1 (colon… (More)
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1987
1987
A Phase I study of caracemide evaluating a short intravenous infusion repeated every 21 days is presented. Patients were entered… (More)
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1987
1987
In recent phase 1 clinical trials, caracemide [N-acetyl-N-(methylcarbamoyloxy)-N-methylurea; NSC-253272] has demonstrated a… (More)
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1986
1986
Preclinical pharmacologic studies of caracemide [N-acetyl-N-(methylcarbamoyloxy)-N'-methylurea; CAR] have demonstrated a marked… (More)
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1984
1984
Caracemide, a new antitumor agent now in clinical trial, was tested against partially purified ribonucleotide reductase from rat… (More)
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