Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

caracemide

Known as: Acetamide, N-[(Methylamino)carbonyl]-N-[[(methylamino)carbonyl]oxy]-(9CI), Acetamide, N-[(methylamino)carbonyl]-N-[[(methylamino)carbonyl]oxy]- (9CI), N-Acetyl-N-(methylcarbamoyloxy)-N'-methylurea 
An agent derived from acetohydroxamic acid with potential antineoplastic activity. Caracemide inhibits ribonuclease reductase, resulting in decreased… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Twenty-four previously untreated, ambulatory patients with advanced colorectal carcinoma were treated with either caracemide (11… Expand
  • table 1
  • table 2
Is this relevant?
2004
2004
Caracemide (NacetylN(methylcarbamoyloxy)N-methylurea) is a nonspecific inhibitor of macromolecular synthesis [1]. It has in vitro… Expand
  • table 1
Is this relevant?
1996
1996
SummaryForty-eight previously untreated, ambulatory patients with advanced or unresectable renal carcinoma were treated with… Expand
  • table 2
  • table I
Is this relevant?
1993
1993
Following administration to rats of a single ip dose (6.6 mg kg-1) of the investigational antitumor agent caracemide (N-acetyl-N… Expand
Is this relevant?
1992
1992
The anticancer drug caracemide, N-acetyl-N,O- di(methylcarbamoyl)hydroxylamine, and one of its degradation products, N-acetyl-O… Expand
Is this relevant?
1990
1990
The antitumor agent caracemide [N-acetyl-N-(methylcarbamoyloxy)-N'-methylurea] has been observed to induce signs of cholinergic… Expand
Is this relevant?
1987
1987
We conducted a phase I trial of caracemide, a new chemotherapeutic agent, which is active in the MX1 (mammary) and CX1 (colon… Expand
Is this relevant?
1987
1987
SummaryA Phase I study of caracemide evaluating a short intravenous infusion repeated every 21 days is presented. Patients were… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
1987
1987
In recent phase 1 clinical trials, caracemide [N-acetyl-N-(methylcarbamoyloxy)-N-methylurea; NSC-253272] has demonstrated a… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • table 1
Is this relevant?
1986
1986
Preclinical pharmacologic studies of caracemide [N-acetyl-N-(methylcarbamoyloxy)-N'-methylurea; CAR] have demonstrated a marked… Expand
Is this relevant?