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cantide

National Institutes of Health

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Phosphorothioate Oligonucleotides

Papers overview

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2012
2012
Antisense Oligonucleotide against hTERT (Cantide) Inhibits Tumor Growth in an Orthotopic Primary Hepatic Lymphoma Mouse Model
Background Human xenograft models, resulting from orthotopic transplantation (implantation into the anatomically correct site) of… 
2012
2012
[Effects of single versus combined use of trastuzumab and cantide on breast cancer cells SKBR3 over-expressing HER2].
OBJECTIVE To evaluate the in vitro cytotoxic effects of cantide or herceptin on human breast cancer SKBR3 cells over-expressing… 
2010
2010
In vitro killing effect of cantide on breast cancer cell strains
Objective To investigate the in vitro killing effect of an antisense oligodeoxynucleotide drug, cantide, on breast cancer cell… 
2010
2010
[Quantitative determination of Cantide, an antisense oligodeoxynucleotide in rhesus monkey plasma using non-gel sieving capillary electrophoresis method].
A dual solid phase extraction (SPE) pretreatment coupling with non-gel sieving capillary electrophoresis (NGCE) analysis method… 
2005
2005
Combined effects of Cantide and chemotherapeutic drugs on inhibition of tumor cells' growth in vitro and in vivo.
AIM To investigate the combination effect of hTERT antisense oligonucleotide "Cantide" and three chemotherapeutic drugs… 
2005
2005
[Quantitative analysis of cantide in plasma by capillary gel electrophoresis].
Cantide is a 20-mer antisense phosphorothioate oligonucleotide that inhibits telomerase catalytic subunit hTERT, pharmacologic… 
2005
2005
Purification of phosphorothioate antisense oligonucleotide Cantide
OBJECTIVE To develop a single step ehromatographic method for large-scale purification of phosphorothioate antisense… 
2005
2005
Combined effects of Cantide and chemotherapeutic drugs on inhibition of tumor cells＇ growth in vitro and in vivo
AIM: To investigate the combination effect of hTERT antisense oligonucleotide "Cantide" and three chemotherapeutic drugs… 
2004
2004
[Determination of antisense phosphorothioate oligonucleotide drug Cantide by capillary gel electrophoresis].
Cantide is a 20-mer antisense phosphorothioate oligonucleotide that inhibits telomerase catalytic subunit hTERT. A capillary gel… 
2003
2003
Antitumor mechanism of antisense cantide targeting human telomerase reverse transcriptase
AIM: To investigate the anti-tumor mechanism of antisenseoligodeoxynucleotide cantide against hTERT.METHODS: Tumor cells were… 
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