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cantide

National Institutes of Health

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Phosphorothioate Oligonucleotides

Papers overview

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2012
2012
Antisense Oligonucleotide against hTERT (Cantide) Inhibits Tumor Growth in an Orthotopic Primary Hepatic Lymphoma Mouse Model
Background Human xenograft models, resulting from orthotopic transplantation (implantation into the anatomically correct site) of… 
2011
2011
[Pharmacokinetics of cantide, an antisense oligonucleotide, and its metabolites in rhesus monkeys].
To study the pharmacokinetics of cantide, an antisense oligonucleotide, and its metabolites after iv gtt administration in rhesus… 
2005
2005
Inhibition of tumor growth and metastasis with antisense oligonucleotides (Cantide) targeting hTERT in an in situ human hepatocellular carcinoma model
AbstractAim:To evaluate the in vivo antitumor effects of Cantide and the combined effect with 5-fluorouracil.Methods:An in situ… 
2005
2005
Combined effects of Cantide and chemotherapeutic drugs on inhibition of tumor cells' growth in vitro and in vivo.
AIM To investigate the combination effect of hTERT antisense oligonucleotide "Cantide" and three chemotherapeutic drugs… 
2005
2005
[Quantitative analysis of cantide in plasma by capillary gel electrophoresis].
Cantide is a 20-mer antisense phosphorothioate oligonucleotide that inhibits telomerase catalytic subunit hTERT, pharmacologic… 
2005
2005
Purification of phosphorothioate antisense oligonucleotide Cantide
OBJECTIVE To develop a single step ehromatographic method for large-scale purification of phosphorothioate antisense… 
2005
2005
Inhibition of tumor growth and metastasis with antisense oligonucleotides （Cantide） targeting hTERT in an in situ human hepatocellular carcinoma model
Aim: To evaluate the in vivo antitumor effects of Cantide and the combined effect with 5-fluorouracil. Methods: An in situ human… 
2004
2004
[Determination of antisense phosphorothioate oligonucleotide drug Cantide by capillary gel electrophoresis].
Cantide is a 20-mer antisense phosphorothioate oligonucleotide that inhibits telomerase catalytic subunit hTERT. A capillary gel… 
Highly Cited
2003
Highly Cited
2003
Calcium/Calmodulin-dependent Protein Kinase II Binds to Raf-1 and Modulates Integrin-stimulated ERK Activation*
Integrin activation generates different signalings in a cell type-dependent manner and stimulates cell proliferation through the… 
2003
2003
Antitumor mechanism of antisense cantide targeting human telomerase reverse transcriptase.
AIM To investigate the anti-tumor mechanism of antisense oligodeoxynucleotide cantide against hTERT. METHODS Tumor cells were… 
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