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cancer procoagulant

Known as: fXase, intrinsic fXase, neoplastic procoagulant 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Cysteine EndopeptidasesNeoplasm Proteins
Factor Xaintrinsic tenase

Papers overview

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2013
2013
The missense Thr211Pro mutation in the factor X activation peptide of a bleeding patient causes molecular defect in the clotting cascade
Summary Factor X (FX) is a vitamin K-dependent coagulation zymogen, which upon activation to factor Xa assembles into the… 
2007
2007
Procoagulant factors in patients with cancer
Abstract Background: Clotting activation and thromboembolic manifestations are common features in patients with cancer. Tumor… 
2005
2005
Down-regulation of Factor IXa in the Factor Xase Complex by Protein Z-dependent Protease Inhibitor*
Protein Z-dependent protease inhibitor (ZPI) is a serpin inhibitor of coagulation factor (F) Xa dependent on protein Z, Ca2+, and… 
2001
2001
Biochemistry of cancer procoagulant.
Cancer procoagulant (CP), EC3.4.22.26, is a cysteine proteinase produced by malignant or fetal tissue. It is a single chain Mr 68… 
Highly Cited
1994
Highly Cited
1994
Cancer procoagulant in the human promyelocytic cell line NB4 and its modulation by all-trans-retinoic acid.
Acute promyelocytic leukemia (APL) cells express different types of procoagulant activity (PCA), including tissue factor (TF… 
1994
1994
Application of cancer procoagulant as an early detection tumor marker
Background. In spite of many advances in the analytical reagents (antibodies), analytical systems, and the clinical application… 
1994
1994
New Immunocapture Enzyme (ICE) Assay for Quantification of Cancer Procoagulant Activity: Studies of Inhibitors
Summary A new, sensitive and specific immunocapture enzyme (ICE) assay for quantitation of the enzymatic activity of cancer… 
1990
1990
Cancer procoagulant in acute lymphoblastic leukemia
In a previous study we characterized cancer procoagulant (CP), a 68 kd cysteine proteinase which directly activates coagulation… 
1987
1987
Several murine metastasizing tumors possess a cysteine proteinase with cancer procoagulant characteristics
Cancer Procoagulant (CP), a cysteine proteinase which triggers blood coagulation by directly activating Factor X (FX) in the… 
Highly Cited
1979
Highly Cited
1979
Comparison of procoagulant activities in extracts of normal and malignant human tissue.
Cancer procoagulant A (CPA) was originally described in extracts of tumor tissue, but whether this represented a quantitative and… 
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