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cAMP response element binding

Known as: CRE binding, cyclic-AMP-responsive element binding, cyclic-AMP response element binding 
Interacting selectively and non-covalently with the cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters… Expand
National Institutes of Health

Papers overview

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2016
2016
Long-term Ameliorative Effects of the Antidepressant Fluoxetine Exposure on Cognitive Deficits in 3 × TgAD Mice
Fluoxetine, a selective serotonin reuptake inhibitor, is neuroprotective; therefore, it has been applied to treat some… Expand
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Highly Cited
2013
Highly Cited
2013
Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor α.
Peroxisome proliferator-activated receptor α (PPARα) is a transcription factor that regulates genes involved in fatty acid… Expand
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Highly Cited
2011
Highly Cited
2011
GSK3β negatively regulates oligodendrocyte differentiation and myelination in vivo.
Glycogen synthase kinase 3β (GSK3β) is an essential integrating molecule for multiple proliferation and differentiation signals… Expand
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Highly Cited
2011
Highly Cited
2011
Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: Involvement of hippocampal plasticity via AKT, CREB and BDNF signaling
In the present study, we investigated whether mild-intensity physical exercise represents a successful strategy to enhance… Expand
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Highly Cited
2010
Highly Cited
2010
Yohimbine Increases Impulsivity Through Activation of cAMP Response Element Binding in the Orbitofrontal Cortex
BACKGROUND Stress can increase impulsivity and has a negative impact on psychiatric outcome. Norepinephrine is heavily implicated… Expand
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2005
2005
Inhibitory effects of the extracts of Sutherlandia frutescens (L.) R. Br. and Harpagophytum procumbens DC. on phorbol ester-induced COX-2 expression in mouse skin: AP-1 and CREB as potential upstream…
Numerous anti-inflammatory agents have been shown to exert chemopreventive activity by targeting cyclooxygenase (COX)-2, a rate… Expand
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Highly Cited
2003
Highly Cited
2003
Increased susceptibility to intermittent hypoxia in aging rats: changes in proteasomal activity, neuronal apoptosis and spatial function.
Obstructive sleep apnea (OSA) is a frequent medical condition characterized by intermittent hypoxia (IH) during sleep, and is… Expand
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2002
2002
Phosphorylation of cAMP response element binding (CREB) protein during hypoxia in cerebral cortex of newborn piglets and the effect of nitric oxide synthase inhibition
Previous studies have shown that hypoxia results in increased phosphorylation of CREB protein that mediates gene expression… Expand
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Highly Cited
1999
Highly Cited
1999
Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors
Tumour suppressor genes and growth regulatory genes are frequent targets for methylation defects that can result in aberrant… Expand
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Highly Cited
1990
Highly Cited
1990
Both the basic region and the 'leucine zipper' domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation.
Second messengers like cAMP can activate the transcription of genes containing consesus cAMP response element (CRE). A 43 kd… Expand
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