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bulaquine

Known as: CDRI 80-53, N'-(3-acetyl-4,5-dihydro-2-furanyl)-N(4)-(6-methoxy-8-quinolyl)-1,4-pentanediamine 
National Institutes of Health

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Broader (1)

Primaquine
analogs & derivatives

Papers overview

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Review
2015
Review
2015
Primaquine or other 8-aminoquinoline for reducing Plasmodium falciparum transmission
Background Mosquitoes become infected with Plasmodium when they ingest gametocyte-stage parasites from an infected person's blood… 
2008
2008
Identification of differentially expressed genes after acute exposure to bulaquine (CDRI 80/53) in mice liver.
Therapeutic agents derived from 8-aminoquinoline possess potent activity against hepatic stages of plasmodia. Bulaquine (CDRI 80… 
2007
2007
In Vitro and In Vivo pharmacokinetic studies of bulaquine (analogue of primaquine), a novel antirelapse antimalarial, in rat, rabbit and monkey—highlighting species similarities and differences
Bulaquine (BQ) is a potent antirelapse antimalarial developed by CDRI, India. Bulaquine was rapidly absorbed in rats and rabbits… 
2006
2006
Safety and tolerability of elubaquine (bulaquine, CDRI 80/53) for treatment of Plasmidium vivax malaria in Thailand.
We conducted a study to compare the safety and tolerability of anti-relapse drugs elubaquine and primaquine against Plasmodium… 
Review
2006
Review
2006
8-Aminoquinolines: future role as antiprotozoal drugs
Purpose of review This review focuses on recent developments on evaluation of 8-aminoquinoline analogs with broader efficacy and… 
Review
2006
Review
2006
ymposium Malaria : Antimalarial resistance and policy ramifications and challenges
Department of Clinical ABSTRACT Pharmacology, Seth G S ‘The National Health Policy 2002” of India and the “Roll Back Malaria… 
2005
2005
Plasmodium cynomolgi: gametocytocidal activity of the anti-malarial compound CDRI 80/53 (elubaquine) in rhesus monkeys.
2004
2004
Preliminary report of the evaluation of the gametocytocidal action of bulaquine, in adult patients with acute, Plasmodium falciparum malaria
In the treatment of human malaria, the 8-aminoquinolines, such as primaquine (PQ), are unique because they exhibit activity… 
2003
2003
HPLC and HPTLC assays for the antimalarial agents chloroquine, primaquine and bulaquine.
2001
2001
Comparative antirelapse efficacy of CDRI compound 80/53 (Bulaquine) vs primaquine in double blind clinical trial
One-year follow-up of malaria patients was undertaken to monitor the antirelapse efficacy of CDRI compound 80/53 (Bulaquine). A… 
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