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budralazine

Known as: 1(2H)-Phthalazinone, (1,3-dimethyl-2-butenylidene)hydrazone, 1-(2-(1,3-dimethyl-2-butenylidene)hydrazino)phthalazine, 4-Methyl-3-penten-2-one (1-phthalazinyl)hydrazone 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (3)

Antihypertensive AgentsHydralazineVasodilator Agents

Narrower (1)

DJ 1461
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1989
1989
Influence of antihypertensive treatment with budralazine on autoregulation of cerebral blood flow in spontaneously hypertensive rats.
We studied the effect of chronic antihypertensive treatment with budralazine on the lower blood pressure limit of cerebral blood… 
1985
1985
Genetic toxicity of several antihypertensive drugs possessing a hydrazine group.
1983
1983
Characterization of the vasodilator action of antihypertensive drug budralazine.
Intravenous injection of 1-[2-(1,3-dimethyl-2-butenylidene)hydrazino]phthalazine (budralazine) to anesthetized dogs resulted in… 
1981
1981
Pre- and postsynaptic alpha-adrenergic effects of the antihypertensive drug budralazine.
Cardiac presynaptic and vascular postsynaptic alpha-adrenergic effects of 1-[2-(1,3-dimethyl-2-butenylidene)hydrazino]phthalazine… 
1981
1981
Hypotensive and cardiovascular action of budralazine in unanesthetized and unrestrained dogs.
In renal hypertensive dogs, 1-[2-(1,3-dimethyl-2-butenylidene)hydrazino]phthalazine (budralazine) at doses of 1 and 2.5 mg/kg p.o… 
1981
1981
Antihypertensive and general pharmacological properties of budralazine.
Antihypertensive and general pharmacological properties of 1-[2-(1,3-dimethyl-2-butenylidene)hydrazino]phthalazine (budralazine… 
1979
1979
Metabolism of budralazine, a new antihypertensive agent, III.
1. [14C]Budralazine (I) administered orally to normotensive and spontaneously hypertensive rats showed no significant difference… 
1978
1978
Pharmacology of budralazine, a new antihypertensive drug.
Antihypertensive and pharmacological properties of budralazine were examined in comparison with other antihypertensive drugs… 
1978
1978
Toxicological studies of 1-[2-(1,3-dimethyl-2-butenylidene)-hydrazino]-phthalazine, a new antihypertensive drug, in mice and rats.
1977
1977
Metabolism of budralazine, a new antihypertensive agent. II. Metabolic pathways of budralazine in rats.
The metabolic pathways of budralazine were studied in vivo and in vitro experiments and characterized as follows ; 1) 3-methyl-s… 
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