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budralazine

Known as: 1(2H)-Phthalazinone, (1,3-dimethyl-2-butenylidene)hydrazone, 1-(2-(1,3-dimethyl-2-butenylidene)hydrazino)phthalazine, 4-Methyl-3-penten-2-one (1-phthalazinyl)hydrazone 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (3)

Antihypertensive AgentsHydralazineVasodilator Agents

Narrower (1)

DJ 1461
analogs & derivatives

Papers overview

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1990
1990
Effects of antihypertensive drugs on experimental cerebral ischemia in spontaneously hypertensive rats.
The effects of antihypertensive drugs on ischemic cerebral damage were investigated using the bilateral carotid artery occlusion… 
1989
1989
[Anti-tachycardiac effect of a direct-acting vasodilator, budralazine].
The present study was undertaken to elucidate the anti-tachycardiac effect of a direct-acting vasodilator, budralazine, using an… 
1986
1986
Cardiovascular effects of budralazine in the dog.
Cardiovascular effects of budralazine were investigated in isolated and cross-circulated dog atrial preparations. When… 
1983
1983
Characterization of the vasodilator action of antihypertensive drug budralazine.
Intravenous injection of 1-[2-(1,3-dimethyl-2-butenylidene)hydrazino]phthalazine (budralazine) to anesthetized dogs resulted in… 
1983
1983
Effects of vasodilators on the platelet aggregation and PGI2 generation of vessel wall
Vasodilator drugs have often been applied clinically to the patients with ischemic heart disease or hypertension, and their… 
1981
1981
Hypotensive and cardiovascular action of budralazine in unanesthetized and unrestrained dogs.
In renal hypertensive dogs, 1-[2-(1,3-dimethyl-2-butenylidene)hydrazino]phthalazine (budralazine) at doses of 1 and 2.5 mg/kg p.o… 
1981
1981
Pre- and postsynaptic alpha-adrenergic effects of the antihypertensive drug budralazine.
Cardiac presynaptic and vascular postsynaptic alpha-adrenergic effects of 1-[2-(1,3-dimethyl-2-butenylidene)hydrazino]phthalazine… 
1979
1979
[3-Hydrazinepyridazine derivatives. III. Synthesis and anti-hypertensive activity of new 3-(2-acylhydrazine)-pyridazine-6-alkylamino substitutes].
The synthesis of 2-(6-dialkylamino-3-pyridazinyl)hydrazinecarboxylates (II) and hydrazides (V) from the corresponding 3-chloro-6… 
1978
1978
Pharmacology of budralazine, a new antihypertensive drug.
Antihypertensive and pharmacological properties of budralazine were examined in comparison with other antihypertensive drugs… 
1976
1976
Metabolism of budralazine, a new antihypertensive agent. I. Identification of the metabolites of budralazine in rats.