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bucolome
Known as:
1-cyclohexyl-5-butylbarbituric acid
, 2,4,6(1H,3H,5H)-Pyrimidnetrione, 5-butyl-1-cyclohexyl-
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Barbital
Barbiturates
Narrower (1)
Paramidine
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Effects of combination therapy with warfarin and bucolome for anticoagulation in patients with atrial fibrillation.
H. Obata
,
Hiroshi Watanabe
,
+4 authors
Y. Aizawa
Circulation Journal
2011
Corpus ID: 8819835
BACKGROUND Bucolome, a nonsteroidal antiinflammatory drug, enhances the effects of warfarin. In the present study, the effects of…
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2005
2005
BUCOLOME, A POTENT BINDING INHIBITOR FOR FUROSEMIDE, ALTERS THE PHARMACOKINETICS AND DIURETIC EFFECT OF FUROSEMIDE: POTENTIAL FOR USE OF BUCOLOME TO RESTORE DIURETIC RESPONSE IN NEPHROTIC SYNDROME
N. Takamura
,
T. Maruyama
,
+6 authors
M. Otagiri
Drug Metabolism And Disposition
2005
Corpus ID: 1184330
To determine whether bucolome (5-n-butyl-1-cyclohexyl-2,4,6-trioxoperhydropyrimidine), a nonsteroidal anti-inflammatory agent…
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2001
2001
The Stereoselective Effects of Bucolome on the Pharmacokinetics and Pharmacodynamics of Racemic Warfarin
Kana Matsumoto
,
S. Ishida
,
+6 authors
M. Shibakawa
Journal of clinical pharmacology
2001
Corpus ID: 33125554
The objective of this study was to investigate the stereoselective influence of bucolome on the pharmacokinetics and…
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1989
1989
Displacement of bilirubin from adult and newborn serum albumin by a drug and fatty acid.
Per Ivarsen
,
Rolf Brodersen
Developmental Pharmacology and Therapeutics
1989
Corpus ID: 453431
Competitive binding of bilirubin and 5-butyl-1-cyclohexylbarbituric acid (bucolome) to human serum albumin was investigated by…
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1985
1985
Bucolome N-glucuronide: purification and identification of a major metabolite of bucolome in rat bile.
K. Mohri
,
T. Uesugi
,
K. Kamisaka
Xenobiotica; the fate of foreign compounds in…
1985
Corpus ID: 33563956
A biliary metabolite of bucolome in rat was isolated and purified by column chromatography. The metabolite has been identified as…
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1982
1982
Increased Nervous System‐Specific Enolases in Rat Plasma and Cerebrospinal Fluid in Bilirubin Encephalopathy Detected by an Enzyme Immunoassay
R. Semba
,
Kanefusa Kato
Journal of Neurochemistry
1982
Corpus ID: 28528048
Abstract: Three forms of enolase isozymes (αα, αγ, and γγ), including nervous system‐specific forms, were measured in the…
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1978
1978
Danger of bucolome in infants with hyperbilirubinaemia. Experimental evidence.
R. Semba
,
H. Sato
,
H. Yamamura
Archives of Disease in Childhood
1978
Corpus ID: 11461934
Effects of bucolome on congenitally jaundiced Gunn rats were examined. Plasma total bilirubin level fell immediately after a…
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1978
1978
INCREASED BILIARY EXCRETION OF OUABAIN INDUCED BY BUCOLOME IN THE RAT
K. Kitani
,
S. Kanai
,
R. Miura
Clinical and Experimental Pharmacology and…
1978
Corpus ID: 24931766
1. Following the intravenous injection of 3H‐ouabain (0.4 or 0.6 mg/100 g body weight) the plasma concentration and biliary…
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1977
1977
Bucolome in prevention of hyperbilirubinaemia in preterm infants.
G. Segni
,
G. Polidori
,
C. Romagnoli
Archives of Disease in Childhood
1977
Corpus ID: 1211588
Fifty preterm babies were randomly assigned to a group given oral bucolome (30 mg/kg per day for 5 days) and a control group…
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1977
1977
Bile-salt-dependent and independent choleresis induced by bucolome in the rat.
K. Kitani
,
Y. Morita
,
R. Miura
,
S. Kanai
Canadian Journal of Physiology and Pharmacology
1977
Corpus ID: 23294591
Choleresis induced by bucolome (BC) (1-cyclohexyl-5-n-butyl-2,4,6-trioxoperhydropyrimidine) was studied in male Wistar rats. [14C…
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