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bucindolol

Known as: 2-(2-Hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)benzonitrile, Benzonitrile, 2-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)-, monohydrochloride, Bucindololum 
 
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Summary The β1-adrenoceptor (β1AR) is the site of action of beta blockers used in the treatment of cardiac-related illnesses. Two… Expand
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES This study sought to assess the effect of angiotensin-converting enzyme (ACE) inhibitors and beta-blockers on all… Expand
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES The goal of this study was to determine the influence of gender on baseline characteristics, response to treatment… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Beta-blocking agents reduce the risk of hospitalization and death in patients with mild-to-moderate heart failure, but… Expand
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Highly Cited
2000
Highly Cited
2000
Clinical studies have shown different effects of β‐blockers on the β‐adrenergic system, tolerability and outcome in patients with… Expand
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Highly Cited
1994
Highly Cited
1994
BACKGROUND Small-scale clinical investigations have demonstrated that single doses of beta-blocking agents can improve left… Expand
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Highly Cited
1991
Highly Cited
1991
BACKGROUND We investigated the effects of bucindolol, a nonselective, non-ISA beta-blocker with mild-vasodilatory properties, in… Expand
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Highly Cited
1990
Highly Cited
1990
The hemodynamic effects of beta-adrenergic blockade with bucindolol, a nonselective beta-antagonist with mild vasodilatory… Expand
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Highly Cited
1990
Highly Cited
1990
PURPOSE Bucindolol is a potent nonselective beta-blocking agent with vasodilatory properties. In this study, we evaluated the… Expand
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Highly Cited
1990
Highly Cited
1990
The sympathetic hyperactivity of congestive heart failure (CHF) may worsen cardiovascular function by down-regulation of… Expand
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