bromobenzarone
National Institutes of Health
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Hepatic metabolism of the uricosuric drug benzbromarone results in the formation of two hydroxilated main metabolites M1 (1…
The uricosuric substance benzbromarone initially was reported to be debrominated to bromobenzarone and benzarone (Yu 1976…
Benzbromarone is one of the three most important uricosuric drugs and widely used in Europe. Initially it was reported to be…
SummaryBenzbromarone is one of the main uricosuric drugs currently used. We determined plasma concentrations of benzbromarone…
Recently we reported that benzbromarone is not debrominated to bromobenzarone and benzarone, but is transformed into two major…
SummaryBenzbromarone, uniformly labelled with tritium by the Wilzbach procedure, was administered orally to 10 patients. No…