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bitopertin

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Purpose/Background Deficits in N-methyl-D-aspartate receptor (NMDAR) function contribute to symptoms and cognitive dysfunction in… 
Review
2015
Review
2015
Objective: We aimed to review research on smoking and mental illness and provide evidence-based guidelines for psychiatrists to… 
Highly Cited
2014
Highly Cited
2014
IMPORTANCE In schizophrenia, the severity of negative symptoms is a key predictor of long-term disability. Deficient signaling… 
2014
2014
Bitopertin (RG1678) is a glycine reuptake inhibitor in phase 3 trials for treatment of schizophrenia. Its clinical oral… 
Review
2014
Review
2014
  • K. Hashimoto
  • Expert opinion on therapeutic targets
  • 2014
  • Corpus ID: 207486466
Introduction: Abnormalities in glutamatergic neurotransmission mediated by N-methyl-d-aspartate (NMDA) are implicated in the… 
Review
2013
Review
2013
Severe psychiatric disorders such as schizophrenia are related to cognitive and negative symptoms, which often are resistant to… 
Review
2013
Review
2013
Evidence-based medicine (EBM) is a broad concept, but the key elements include the incorporation of clinical judgment (which… 
2013
2013
Deficient N-methyl-D-aspartate (NMDA) receptor transmission is thought to underlie schizophrenia. An approach for normalizing…