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bitopertin

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Deficits in N-methyl-d-aspartate-type (NMDAR) function contribute to cognitive deficits in schizophrenia, particularly… Expand
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Highly Cited
2017
Highly Cited
2017
BACKGROUND There is currently no standard of care for treatment of negative symptoms of schizophrenia, although some previous… Expand
2016
2016
BACKGROUND Many patients with schizophrenia require high doses of medication for their ongoing psychotic symptoms. Glutamate… Expand
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Review
2015
Review
2015
Objective: We aimed to review research on smoking and mental illness and provide evidence-based guidelines for psychiatrists to… Expand
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Highly Cited
2014
Highly Cited
2014
IMPORTANCE In schizophrenia, the severity of negative symptoms is a key predictor of long-term disability. Deficient signaling… Expand
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Highly Cited
2014
Highly Cited
2014
Bitopertin is a glycine reuptake inhibitor postulated to improve N-methyl-d-aspartate receptor hypofunction by increasing… Expand
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2014
2014
  • D. Goff
  • JAMA psychiatry
  • 2014
  • Corpus ID: 2042984
In this issue, Umbricht and colleagues1 reported improvement of negative symptoms of schizophrenia associated with 2 of 3 doses… Expand
Review
2014
Review
2014
  • L. Citrome
  • The Journal of clinical psychiatry
  • 2014
  • Corpus ID: 20705056
Current treatments for schizophrenia, although effective for positive symptoms, have not proven as effective for negative… Expand
Review
2013
Review
2013
Severe psychiatric disorders such as schizophrenia are related to cognitive and negative symptoms, which often are resistant to… Expand
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Review
2013
Review
2013
Evidence-based medicine (EBM) is a broad concept, but the key elements include the incorporation of clinical judgment (which… Expand
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