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bitopertin

 
National Institutes of Health

Papers overview

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2017
2017
BACKGROUND There is currently no standard of care for treatment of negative symptoms of schizophrenia, although some previous… Expand
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2016
2016
BACKGROUND Many patients with schizophrenia require high doses of medication for their ongoing psychotic symptoms. Glutamate… Expand
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2015
2015
AbstractBackground and ObjectivesWe propose a strategy for studying ethnopharmacology by conducting sequential physiologically… Expand
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Highly Cited
2014
Highly Cited
2014
IMPORTANCE In schizophrenia, the severity of negative symptoms is a key predictor of long-term disability. Deficient signaling… Expand
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Highly Cited
2014
Highly Cited
2014
Bitopertin is a glycine reuptake inhibitor postulated to improve N-methyl-d-aspartate receptor hypofunction by increasing… Expand
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2014
2014
In this issue, Umbricht and colleagues1 reported improvement of negative symptoms of schizophrenia associated with 2 of 3 doses… Expand
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Review
2014
Review
2014
  • Leslie Citrome
  • The Journal of clinical psychiatry
  • 2014
  • Corpus ID: 20705056
Current treatments for schizophrenia, although effective for positive symptoms, have not proven as effective for negative… Expand
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2014
2014
Bitopertin (RG1678) is a glycine reuptake inhibitor in phase 3 trials for treatment of schizophrenia. Its clinical oral… Expand
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Review
2013
Review
2013
Severe psychiatric disorders such as schizophrenia are related to cognitive and negative symptoms, which often are resistant to… Expand
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2013
2013
Deficient N-methyl-D-aspartate (NMDA) receptor transmission is thought to underlie schizophrenia. An approach for normalizing… Expand
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