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bis(12)-hupyridone

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Fibrillar aggregates of β-amyloid protein (Aβ) is the main constituent of senile plaques and considered to be one of the… Expand
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2013
2013
Bis(12)-hupyridone (B12H), derived from the Chinese medicinal component huperzine A, was originally designed as a novel… Expand
2012
2012
Alzheimer’s disease (AD), clinically characterized by progressive impairments of memory, cognitive functions and behaviors, is a… Expand
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2011
2011
The cause of many neurodegenerative disorders can be ascribed to the loss of functional neurons, and thus agents capable of… Expand
2011
2011
The objective of the present study was to elucidate the mechanisms of intestinal transport of bis(12)‐hupyridone (B12H) to… Expand
2011
2011
Oxidative stress-induced apoptosis plays a critical role in the pathogenesis of various neurodegenerative disorders. In this… Expand
2011
2011
The activation of N-methyl-d-aspartate (NMDA) receptors by excessive release of glutamate is involved in the pathogenesis of… Expand
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2009
2009
A rapid and simple method of high performance liquid chromatography with UV detection for the quantification of bis(12… Expand
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2008
2008
  • H. Yu, W. Li, +8 authors Yi-Fan Han
  • Journal of pharmaceutical and biomedical analysis
  • 2008
  • Corpus ID: 40675146
The lipophilicity and solubility profiles of bis(12)-hupyridone (B12H) and bis(7)-tacrine (B7T), two novel acetylcholinesterase… Expand
Review
2007
Review
2007
Alzheimer's disease (AD) is linked to cholinergic deficiency and the overactivation of glutamate receptors. The… Expand