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biotin synthase

Known as: biotin synthetase 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

BIO2 protein, Arabidopsis
biotin synthase activity

Broader (1)

sulfurtransferase

Papers overview

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Highly Cited
2010
Highly Cited
2010
Biotin synthase exhibits burst kinetics and multiple turnovers in the absence of inhibition by products and product-related biomolecules.
Biotin synthase (BS) is a member of the "SAM radical" superfamily of enzymes, which catalyze reactions in which the reversible or… Expand
2008
2008
9-Mercaptodethiobiotin is formed as a competent catalytic intermediate by Escherichia coli biotin synthase.
Biotin synthase (BS) catalyzes the oxidative addition of a sulfur atom to dethiobiotin (DTB) to generate the biotin thiophane… Expand
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2006
2006
Role of the [2Fe-2S]2+ cluster in biotin synthase: mutagenesis of the atypical metal ligand arginine 260.
Biotin synthase (BS) is an S-adenosylmethionine (AdoMet)-dependent radical enzyme that catalyzes the addition of sulfur to… Expand
2003
2003
Control of adenosylmethionine-dependent radical generation in biotin synthase: a kinetic and thermodynamic analysis of substrate binding to active and inactive forms of BioB.
Biotin synthase (BS) is an AdoMet-dependent radical enzyme that catalyzes the insertion of sulfur into saturated C6 and C9 atoms… Expand
Highly Cited
2001
Highly Cited
2001
Spectroscopic changes during a single turnover of biotin synthase: destruction of a [2Fe-2S] cluster accompanies sulfur insertion.
Biotin synthase catalyzes the insertion of a sulfur atom between the saturated C6 and C9 carbons of dethiobiotin. Catalysis… Expand
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2001
2001
The iron-sulfur center of biotin synthase: site-directed mutants
Abstract. Biotin synthase contains an essential [4Fe-4S]+ cluster that is thought to provide an electron for the cleavage of S… Expand
1997
1997
Sequence Analysis of a Near‐subtelomeric 35·4 kb DNA Segment on the Right Arm of Chromosome VII from Saccharomyces cerevisiae Carrying the MAL1 Locus Reveals 15 Complete Open Reading Frames…
The nucleotide sequence of 35 400 bp at approximately 10 kb from the right telomere of chromosome VII was determined. The segment… Expand
1996
1996
Isolation and characterization of the Erwinia herbicola bio operon and the sequences of the bioA and bioB genes.
The biotin operon of Erwinia herbicola was cloned and characterized. The operon consists of five genes arranged in the order… Expand
1989
1989
Cloning of the biotin synthetase gene from Bacillus sphaericus and expression in Escherichia coli and Bacilli.
Biotin synthetase (BS) catalyses the biotransformation of dethiobiotin (DTB) to biotin. Here we report the cloning… Expand
1982
1982
Mode of action of the biotin antimetabolites actithiazic acid and alpha-methyldethiobiotin.
Actithiazic acid and alpha-methyldethiobiotin inhibited the conversion of dethiobiotin to biotin resting-cell suspensions of… Expand
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