bevirimat

Known as: 3-O-(3',3'-dimethylsuccinyl) betulinic acid, 3-O-(3',3'-dimethylsuccinyl)betulinic acid 
A drug derived from a betulinic acid-like compound, first isolated from the Chinese herb Syzygium claviflorum, with activity against human… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2016
051020012016

Papers overview

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2013
2013
Bevirimat (1, BVM) is an anti-HIV agent that blocks HIV-1 replication by interfering with HIV-1 Gag-SP1 processing at a late… (More)
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2011
2011
Maturation of nascent virions, a key step in retroviral replication, involves cleavage of the Gag polyprotein by the viral… (More)
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2010
2010
Bevirimat (BVM) is the first of a new class of anti-HIV drugs with a novel mode of action known as maturation inhibitors. BVM… (More)
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2010
2010
OBJECTIVE Bevirimat is the first drug of a new class of antivirals that hamper the maturation of HIV. The objective of this study… (More)
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2009
2009
Maturation inhibitors are a new class of antiretroviral drugs. Bevirimat (BVM) was the first substance in this class of… (More)
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2007
2007
Bevirimat [3-O-(3',3'-dimethylsuccinyl)betulinic acid] is the first in a new class of anti-human immunodeficiency virus (HIV… (More)
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2006
2006
3-O-(3',3'-dimethylsuccinyl)betulinic acid (PA-457 or bevirimat) potently inhibits human immunodeficiency virus type 1 (HIV-1… (More)
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2006
2006
3-O-(3',3'-dimethylsuccinyl) betulinic acid, also termed PA-457 or DSB, is a novel HIV-1 inhibitor that blocks virus maturation… (More)
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Highly Cited
2003
Highly Cited
2003
New HIV therapies are urgently needed to address the growing problem of drug resistance. In this article, we characterize the… (More)
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2001
2001
Betulinic acid, a triterpenoid isolated from the methyl alcohol extract of the leaves of Syzigium claviflorum, was found to have… (More)
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