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beta-amyloid formation

Known as: beta-amyloid polypeptide formation from APP, beta-amyloid polypeptide formation from amyloid precursor protein 
The generation of beta-amyloid by cleavage of the amyloid precursor protein (APP). [GOC:mah]
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Infrared study of the effect of hydration on the amide I band and aggregation properties of helical peptides.
The amide I' band of a polypeptide is sensitive not only to its secondary structure content but also to its environment. In this… 
Review
2007
Review
2007
Beta-amyloidbased immunotherapy as a treatment of Alzheimers disease.
The pathology of Alzheimer's disease shows a significant correlation between beta-amyloid peptide conformation and the clinical… 
Highly Cited
2006
Highly Cited
2006
Self-association of Collagen Triple Helic Peptides into Higher Order Structures*
Interest in self-association of peptides and proteins is motivated by an interest in the mechanism of physiologically higher… 
2005
2005
Generation of anti-beta-amyloid antibodies via phage display technology towards Alzheimer's disease vaccination.
Highly Cited
2004
Highly Cited
2004
Beta‐secretase BACE1 is differentially controlled through muscarinic acetylcholine receptor signaling
The β‐amyloid peptides derived by proteolytic cleavage from the amyloid precursor protein (APP) play a major role in the… 
2002
2002
Generation and brain delivery of anti-aggregating antibodies against beta-amyloid plaques using phage display technology.
Antibodies towards the N-terminal region of the beta-amyloid peptide bind to beta-amyloid fibrils, leading to their… 
2000
2000
Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site.
A series of inhibitors of beta-amyloid formation have been developed based on the beta-secretase cleavage site (VNL-DA) of the… 
Highly Cited
1999
Highly Cited
1999
High affinity binding of monoclonal antibodies to the sequential epitope EFRH of β-amyloid peptide is essential for modulation of fibrillar aggregation
1996
1996
Molecular Membrane Interactions of a Phospholipid Metabolite. Implications for Alzheimer's Disease Pathophysiology a
Alzheimers's disease is characterized by changes in phospholipid metabolism leading to a perturbation in the levels of… 
1991
1991
Isolation of baculovirus-derived secreted and full-length beta-amyloid precursor protein.
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