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berberrubine

National Institutes of Health

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Broader (1)

Berberine
analogs & derivatives

Papers overview

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Highly Cited
2018
Highly Cited
2018
Berberrubine attenuates mucosal lesions and inflammation in dextran sodium sulfate-induced colitis in mice
Ulcerative colitis (UC) is a chronic relapsing disease without satisfactory treatments, in which intestinal inflammation and… 
Highly Cited
2014
Highly Cited
2014
Berberine metabolites could induce low density lipoprotein receptor up-regulation to exert lipid-lowering effects in human hepatoma cells.
Highly Cited
2013
Highly Cited
2013
Tissue Distribution of Berberine and Its Metabolites after Oral Administration in Rats
Berberine (BBR) has been confirmed to have multiple bioactivities in clinic, such as cholesterol-lowering, anti-diabetes… 
Highly Cited
2012
Highly Cited
2012
Cytotoxicity and antihyperglycemic effect of minor constituents from Rhizoma Coptis in HepG2 cells.
Highly Cited
2011
Highly Cited
2011
Synthesis of 9-substituted derivatives of berberine as anti-HIV agents.
Highly Cited
2006
Highly Cited
2006
Synthesis, DNA-binding affinities, and binding mode of berberine dimers.
Highly Cited
2006
Highly Cited
2006
Pharmacokinetics of Berberine and Its Main Metabolites in Conventional and Pseudo Germ-Free Rats Determined by Liquid Chromatography/Ion Trap Mass Spectrometry
Berberine (Ber) and its main metabolites were identified and quantified using liquid chromatography/electrospray ionization/ion… 
Highly Cited
2005
Highly Cited
2005
Synthesis of linked berberine dimers and their remarkably enhanced DNA-binding affinities.
Highly Cited
2005
Highly Cited
2005
Spectrometric studies of cytotoxic protoberberine alkaloids binding to double-stranded DNA.
Highly Cited
1998
Highly Cited
1998
Induction of topoisomerase II-mediated DNA cleavage by a protoberberine alkaloid, berberrubine.
Topoisomerase II is the cytotoxic target for a number of clinically relevant antitumor drugs. Berberrubine, a protoberberine… 
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