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berberrubine

 
National Institutes of Health

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2 relations

Broader (1)

Berberine
analogs & derivatives

Papers overview

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2018
2018
Berberrubine attenuates mucosal lesions and inflammation in dextran sodium sulfate-induced colitis in mice
Ulcerative colitis (UC) is a chronic relapsing disease without satisfactory treatments, in which intestinal inflammation and… Expand
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2015
2015
Pharmacokinetics in rats and tissue distribution in mouse of berberrubine by UPLC-MS/MS.
Berberrubine is an isoquinoline alkaloid isolated from Berberis vulgaris L, and it is readily derived from berberine. In this… Expand
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2014
2014
Berberine and its metabolites: relationship between physicochemical properties and plasma levels after administration to human subjects.
Berberine (1) is an alkaloid used widely in the treatment of several diseases. However, its physicochemical properties… Expand
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Highly Cited
2013
Highly Cited
2013
Tissue Distribution of Berberine and Its Metabolites after Oral Administration in Rats
Berberine (BBR) has been confirmed to have multiple bioactivities in clinic, such as cholesterol-lowering, anti-diabetes… Expand
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Highly Cited
2012
Highly Cited
2012
Cytotoxicity and antihyperglycemic effect of minor constituents from Rhizoma Coptis in HepG2 cells.
Generally, berberine, coptisine, palmatine, and jatrorrhizine were considered as the main bio-active compounds in Rhizoma Coptis… Expand
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2006
2006
Synthesis of 13-(substituted benzyl) berberine and berberrubine derivatives as antifungal agents.
By introducing various aromatic groups in 13-C of berberine and berberrubine, a series of 13-(substituted benzyl) berberine and… Expand
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Highly Cited
2006
Highly Cited
2006
Pharmacokinetics of Berberine and Its Main Metabolites in Conventional and Pseudo Germ-Free Rats Determined by Liquid Chromatography/Ion Trap Mass Spectrometry
Berberine (Ber) and its main metabolites were identified and quantified using liquid chromatography/electrospray ionization/ion… Expand
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2002
2002
Down-regulation of DNA topoisomerase IIalpha in human colorectal carcinoma cells resistant to a protoberberine alkaloid, berberrubine.
Berberrubine, a protoberberine alkaloid that exhibits antitumor activity in animal models, has been identified as a specific… Expand
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1998
1998
Induction of topoisomerase II-mediated DNA cleavage by a protoberberine alkaloid, berberrubine.
Topoisomerase II is the cytotoxic target for a number of clinically relevant antitumor drugs. Berberrubine, a protoberberine… Expand
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1976
1976
Antitumor activity of berberrubine derivatives.
The antitumor activity of berberine, berberrubine, and their derivatives against sarcoma-180 ascites was determined by the total… Expand
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