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benzamidoxime

National Institutes of Health

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Benzamidines

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2014
2014
Cyclopalladated complexes derived from benzamidoxime.
Cyclopalladated benzamidoxime complexes [Pd{C,N-C6H4{C(NH2)[double bond, length as m-dash]NOH}-2}Cl(L)] (L = PTol3, Tol = C6H4Me… 
2006
2006
Oxygen-insensitive enzymatic reduction of oximes to imines.
2005
2005
Reduction of sulfamethoxazole and dapsone hydroxylamines by a microsomal enzyme system purified from pig liver and pig and human liver microsomes.
2005
2005
Metabolism of benzamidoxime (N-hydroxyamidine) in human hepatocytes and role of UDP-glucuronosyltransferases
N-Hydroxyamidines (amidoximes) can act as pro-drugs of amidines (e.g. ximelagatran, a novel direct thrombin inhibitor). This… 
2004
2004
Thrombin inhibitors built on an azaphenylalanine scaffold.
2004
2004
Solid-phase synthesis of 5-isoxazol-4-yl-[1,2,4]oxadiazoles.
A library of isoxazole and 1,2,4-oxadiazole-containing diheterocyclic compounds has been prepared. Our strategy was explored in… 
1993
1993
Biotransformations of Benzamidine and Benzamidoxime in vivo
After administration of benzamidine (1) or benzamidoxime (2), respectively, to rats and rabbits, plasma from rats and rabbits as… 
1988
1988
Enzymatic Reduction of Benzamidoxime to Benzamidoxine
Strongly basic amidine functions are components of numerous active principles. Our investigations on the biotransformations of… 
1988
1988
Genotoxic activities of benzamidine and itsN-hydroxylated metabolite benzamidoxime inSalmonella typhimurium and mammalian cells
SummaryThe genotoxic potentials of benzamidine and benzamidoxime were determined to study the toxicological relevance of the… 
1987
1987
Characteristics of the microsomal N-hydroxylation of benzamidine to benzamidoxime.
1. A simple and fast h.p.l.c. analysis of benzamidoxime formed by microsomal N-hydroxylation of benzamidine is presented which is… 
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