bendamustine

Known as: 5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric Acid, Bendamustin 
The active ingredient in a drug that is used to treat chronic lymphocytic leukemia (CLL), to treat slow-growing B-cell non-Hodgkin lymphoma (NHL… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
PURPOSE We investigated the safety and efficacy of bendamustine and rituximab (BR) in previously untreated patients with chronic… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE The objective of this trial was to evaluate safety and efficacy of bendamustine combined with rituximab (BR) in patients… (More)
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Highly Cited
2011
Highly Cited
2011
Given the significant activity and tolerability of bendamustine, rituximab, and bortezomib in patients with relapsed indolent and… (More)
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Highly Cited
2011
Highly Cited
2011
In lymphocytes, the phosphoinositide 3'-kinase (PI3K) isoform p110δ (PI3Kδ) transmits signals from surface receptors, including… (More)
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Review
2009
Review
2009
Bendamustine is a unique cytotoxic agent with structural similarities to alkylating agents and antimetabolites, but which is non… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Bendamustine has shown clinical activity in patients with disease refractory to conventional alkylator chemotherapy. The… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Bendamustine HCl is a bifunctional mechlorethamine derivative with clinical activity in the treatment of non-Hodgkin's… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE The aim of this multicenter-study was to evaluate the progression-free survival, response rate and toxicity of the… (More)
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Highly Cited
2001
Highly Cited
2001
Bendamustine, an alkylating agent without cross-resistance to cyclophosphamide is active in a variety of lymphoproliferative and… (More)
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